Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
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From passive consumers to critical evaluators: promoting media literacy in animal science. [PDF]
Transl Anim SciBowhay CM.
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
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Beyond Awareness: The Critical Need for Actionable Strategies to Bridge the Knowledge-Practice Gap in Hepatitis B Prevention. [PDF]
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What AI Cannot Teach: An Epistemological Reconceptualisation of the Nurse Educator Role Based on an Analysis of Carper's Ways of Knowing. [PDF]
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Survey on academic self-efficacy, academic stress, critical thinking, performance expectations, and students' AI dependency. [PDF]
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Mindfulness-based cognitive therapy as a psychological strategy for mitigating emotional exhaustion among critical care nurses. [PDF]
J Educ Health PromotJazan HF, Mohammed SH.
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Letter to the Editor: Chest X-ray-based severity scores in COVID-19 - what do they tell us about oxygen needs? [PDF]
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