Results 61 to 70 of about 7,934,690 (311)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Frontiers in MedicineObjectiveThis systematic review and meta-analysis assessed the impact of shared decision-making on critically ill patients, focusing on outcomes such as mortality, intensive care unit (ICU) and hospital length of stay (LOS), and mental health symptoms in
Yangyang Wang +8 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Operationalizing radical hope: Broadening whole-child approaches to restructure the whole system
Journal of Childhood, Education & SocietyAlthough a “holistic” tenet of equitable early childhood education and care, focusing on the whole-child overlooks how systems maintain inequality. Predicated on individual-level interventions, the whole-child approach prioritizes “fixing” children, but ...
Mona M. Abo-Zena +3 more
doaj +1 more source
JAMA: The Journal of the American Medical Association, 1897 Clyde, N. Y., July 28, 1897. To the Editor: —In the number for July 24, page 196,I notice under the title " The Jubilee Meeting," that among your exchanges there is one journal, Buffalo Medical and Surgical , which is deeply grieved that the representative of the anarchistic element of the profession of this State—" president of the Medical Society ...
openaire +1 more source
Practices for securing critical information assets. [PDF]
, 2000 "January 2000"--P.
United States. Critical Infrastructure Assurance Office
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source