Results 71 to 80 of about 531,090 (261)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Hybrid Multi-Objective Artificial Bee Colony for Flexible Assembly Job Shop with Learning Effect

open access: yesMathematics
The flexible job shop scheduling problem is a typical and complex combinatorial optimization problem. In recent years, the assembly problem in job shop scheduling problems has been widely studied.
Zhaosheng Du, Junqing Li, Jiake Li
doaj   +1 more source

Algorithms as culture: Some tactics for the ethnography of algorithmic systems

open access: yesBig Data & Society, 2017
This article responds to recent debates in critical algorithm studies about the significance of the term “algorithm.” Where some have suggested that critical scholars should align their use of the term with its common definition in professional computer ...
Nick Seaver
doaj   +1 more source

Studying topological order and Ising criticality with tensor network algorithms

open access: yes, 2021
Tensor network algorithms have emerged as a new approach in simulating strongly correlated quantum many-body systems. In this thesis, we focus on the infinite projected entangled state (iPEPS), a tensor network ansatz for two-dimensional quantum models in the thermodynamic limit. This thesis contains the results out of two main research lines.
openaire   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

GPU Parallel-Rate Exponential Integrator Algorithm for Efficient Simulation of Power Electronic Systems

open access: yesIEEE Open Access Journal of Power and Energy
Electromagnetic transient (EMT) simulation of power electronic converters is critical for analysis, design, and fast control prototyping of power and energy systems.
Jared Paull   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Machine learning for medical image classification

open access: yesAcademia Medicine
This review article focuses on the application of machine learning (ML) algorithms in medical image classification. It highlights the intricate process involved in selecting the most suitable ML algorithm for predicting specific medical ...
Gazi Husain   +5 more
doaj   +1 more source

Berezinskii-Kosterlitz-Thouless phase transition from lattice sine-Gordon model

open access: yesEPJ Web of Conferences, 2018
We obtain nonperturbative results on the sine-Gordon model using the lattice field technique. In particular, we employ the Fourier accelerated hybrid Monte Carlo algorithm for our studies.
Giedt Joel, Flamino James
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

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