Results 261 to 270 of about 14,005,591 (363)

Functional Connectivity Associations With Markers of Disease Progression in GRN Pathogenic Variant Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan, Stephanie A. Chu, Suvi Häkkinen, Liwen Zhang, David McFall, Jonathan D. Rohrer, Jesse A. Brown, Alex J. Lee, Kristen Fernhoff, Lorenzo Pasquini, Katherine P. Rankin, Maria Luisa Mandelli, Maria Luisa Gorno‐Tempini, Jennifer S. Yokoyama, Virginia E. Sturm, Brian Appleby, Bradford C. Dickerson, Kimiko Domoto‐Reilly, Tatiana Foroud, Daniel H. Geschwind, Nupur Ghoshal, Neill R. Graff‐Radford, Ging‐Yuek Robin Hsiung, Eric J. Huang, Edward Huey, Kejal Kantarci, Irene Litvan, Ian R. Mackenzie, Mario F. Mendez, Chiadi U. Onyike, Leonard Petrucelli, Eliana Marisa Ramos, Erik D. Roberson, Julio C. Rojas, Maria Carmela Tartaglia, Arthur W. Toga, Sandra Weintraub, Leah K. Forsberg, Hilary W. Heuer, Brad F. Boeve, Adam L. Boxer, Howard J. Rosen, Bruce L. Miller, Fermin Moreno, William W. Seeley, Suzee E. Lee, on behalf of the ALLFTD Consortium   +46 more
wiley   +1 more source

Critical Care of the Adult With Congenital Heart Disease. [PDF]

JACC Adv
Valle CW, Garfinkel AC, Buber J, Romfh AW, Elliott AM, Menachem JN, Nelson J, Laussen PC, Heggie J, Dezfulian C, Morrow D, Valente AM, American College of Cardiology Critical Care Cardiology Section and Adult Congenital and Pediatric Cardiology Section.   +12 more
europepmc   +1 more source

Practice Recommendations for Genetic Testing of Ataxias

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Over the past decade, significant advances in genetic testing for ataxia have improved diagnostic accuracy, informed clinical trial eligibility, guided treatment decisions, and enabled cascade testing of at‐risk relatives. While guidance exists for other neurogenetic conditions, there are no standardized guidelines on genetic ...
Sharan R. Srinivasan, Amy D. Mook, Michelle Rochman, Jin Yun Helen Chen, Weiyi Mu, George R. Wilmot, Liana S. Rosenthal, Wendy R. Uhlmann   +7 more
wiley   +1 more source

Critical Care Physicians' Perspectives on Nudging in Communication.

JAMA Netw Open
Soled DR, Cummings CL, Berbert LM, Williams DN, Feldman WB, Truog RD, Rubin EB.   +6 more
europepmc   +1 more source

Gamification of Critical Care Medical Education: ICUlympics. [PDF]

ATS Sch
Danckers M, Dasgupta R, Norris T, Acosta Rullan JM, Miret R, Wahood W, Ganthier J, Neralla A, Kuang K, Cabrera R, Lee IM, Zapata D, Diaz R, Kelly WF.   +13 more
europepmc   +1 more source

Implementation of Artifact Detection in Critical Care: A Methodological Review [PDF]

, 2013
Shermeen Nizami, James R. Green, Carolyn McGregor, Shermeen Nizami, James R. Green, Carolyn McGregor   +5 more
openalex   +1 more source

Cognitive Impairment in Multiple Sclerosis: The Role of Clinical and Sociodemographic Factors ‐ A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment (CI) affects the quality of life in multiple sclerosis (MS). Identifying influencing factors is key to improving CI monitoring. This systematic review and meta‐analysis examines clinical and sociodemographic variables impacting the cognitive screening Symbol Digit Modalities Test (SDMT) performance across MS ...
Katalin Lugosi, Marie A. Engh, Tamás Kói, Zsolt Molnár, Gábor Csukly, Klaudia Horváth, Emma Hargitai, Péter Hegyi, Zsolt Mezei   +8 more
wiley   +1 more source

South‒South research collaborations in critical care. [PDF]

Crit Care Sci
Cavalcanti AB, Siaw-Frimpong M, Souza DC, Hernandez G, Hashmi M, Salluh JIF.   +5 more
europepmc   +1 more source

Effect of the Communication Board on Communication Pattern among Intubated Patients in the Critical Care Unit

, 2015
M. Anbu, Kumari M. J, Tarun Kumar Dutta, Angeline Mary Sheela S.   +3 more
openalex   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source