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Critical Care Medicine [PDF]

open access: bronzeAnesthesiology, 2010
The year of 2009∼2010 brought a number of concepts and new ideas were evaluated with promising results. However, some studies that challenged many beliefs. In acute respiratory distress syndrome (ARDS), recent clinical studies took into consideration of pathophysiologic changes of respiratory system compliance.
Jean Mantz, Timothy J. Brennan
  +12 more sources

Discovery of data quality issues in electronic health records: profound consequences for critical care medicine applications - a systematized review. [PDF]

open access: goldCrit Care
de Andrade JBC   +7 more
europepmc   +2 more sources

Chinese expert consensus on diagnosis and treatment of trauma-induced hypercoagulopathy

open access: yesMilitary Medical Research, 2021
Trauma-induced coagulopathy (TIC) is caused by post-traumatic tissue injury and manifests as hypercoagulability that leads to thromboembolism or hypocoagulability that leads to uncontrollable massive hemorrhage.
Jing-Chun Song   +7 more
doaj   +1 more source

Role of Cholinergic Anti-Inflammatory Pathway in Protecting Sepsis-Induced Acute Lung Injury through Regulation of the Conventional Dendritic Cells

open access: yesMediators of Inflammation, 2022
Background. The cholinergic anti-inflammatory pathway connects the immune response system and the nervous system via the vagus nerve. The key regulatory receptor is the α7-subtype of the nicotinic acetylcholine receptor (α7nAChR).
Ruiting Li   +11 more
doaj   +1 more source

circ-Katnal1 Enhances Inflammatory Pyroptosis in Sepsis-Induced Liver Injury through the miR-31-5p/GSDMD Axis

open access: yesMediators of Inflammation, 2022
Background. Sepsis is a systemic inflammatory response that can elicit organ dysfunction as well as circulatory diseases in serious cases. When inflammatory responses are especially dysregulated, severe complications can arise, including sepsis-induced ...
Kai Kang   +8 more
doaj   +1 more source

High-Flow Nasal Oxygen versus Noninvasive Ventilation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients: A Meta-Analysis of Randomized Controlled Trials

open access: yesCanadian Respiratory Journal, 2023
Background. High-flow nasal cannula (HFNC) can be used in stable chronic obstructive pulmonary disease (COPD) patients, but the effect of HFNC on clinical outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is ...
Yanping Du   +11 more
doaj   +1 more source

Combined Age with Mean Decrease Rates of Total Bilirubin and MELD Score as a Novel and Simple Clinical Predictor on 90-Day Transplant-Free Mortality in Adult Patients with Acute Liver Failure Undergoing Plasma Exchange: A Single-Center Retrospective Study

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2023
Background. Acute liver failure (ALF), previously known as fulminant hepatic failure, has become a common, rapidly progressive, and life-threatening catastrophic hepatic disease in intensive care unit (ICU) due to the continuous increase in drug abuse ...
Di Jin   +12 more
doaj   +1 more source

Mesenchymal Stem Cell-Secreted TGF-β1 Restores Treg/Th17 Skewing Induced by Lipopolysaccharide and Hypoxia Challenge via miR-155 Suppression

open access: yesStem Cells International, 2022
Background. Regulatory T cell (Treg)/T helper (Th) 17 skewing is important in the development of acute respiratory distress syndrome (ARDS). Immunomodulatory effects of mesenchymal stem cell- (MSC-) secreted transforming growth factor- (TGF-) β1 on CD4 ...
Ming Xue   +8 more
doaj   +1 more source

Relationship between Nonhepatic Serum Ammonia Levels and Sepsis-Associated Encephalopathy: A Retrospective Cohort Study

open access: yesEmergency Medicine International, 2023
Objectives. Nonhepatic hyperammonemia often occurs in patients with sepsis. Ammonia plays an essential role in the occurrence of hepatic encephalopathy.
Pei Wang   +8 more
doaj   +1 more source

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