Results 101 to 110 of about 2,745,548 (338)

The Impact of Hand Edema on Weaning From Mechanical Ventilation in ICU Patients: A Single Center Nested Case-Control Study

International Journal of Clinical Practice
Conclusion: The occurrence of hand edema in ICU patients on mechanical ventilation increases the risk of weaning failure.
Dingye Wu, Junfeng Heng, Fengming Liang, Tao Zhou, Qiuhui Wang, Hongyang Xu   +5 more
doaj   +1 more source

Inadequate Critical Care Curriculum in Pediatric Emergency Medicine Fellowships [PDF]

, 1994
Jonathan Wasserberger, Gary J. Ordog, William C. Shoemaker   +2 more
openalex   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Metabolomic Profiling by UPLC-QTOF/MS Reveals Potential Biomarkers and Metabolic Alterations in Pediatric Septic Shock

Journal of Inflammation Research
Changxue Xiao,* Chenhao Wang,* Sa Wang, Feng Xu, Yingfu Chen Department of Critical Care Medicine, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of ...
Xiao C, Wang C, Wang S, Xu F, Chen Y
doaj  

Factores de riesgo asociados a Sepsis Nosocomial en recién nacidos pre termino del Servicio de Neonatología, Hospital General Dr. Nicolás San Juan Un estudio de casos [PDF]

, 2014
Las definiciones de sepsis y los procesos relacionados con ̩sta se introdujeron inicialmente en los adultos. En 1992 se reúne el consenso de la American College of Critical Care Medicine y Society of Critical Care Medicine (por sus siglas en ingles: ACCM-
Lugo Trampe, Aldo, Santiago Alcántara, Elia   +1 more
core  

“Bridging the Gap” Everything that Could Have Been Avoided If We Had Applied Gender Medicine, Pharmacogenetics and Personalized Medicine in the Gender-Omics and Sex-Omics Era [PDF]

, 2019
Gender medicine is the first step of personalized medicine and patient-centred care, an essential development to achieve the standard goal of a holistic approach to patients and diseases.
BELLINI, Tiziana, BONACCORSI, Gloria, BRAMANTI, Barbara, Carè, Alessandra, GEMMATI, Donato, MANFRINATO, Maria Cristina, PIVA, Maria Roberta, TISATO, Veronica, TRENTINI, Alessandro, VARANI, Katia   +9 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Unleashing Top-of-License Registered Nurse Practice: An Integrative Review [PDF]

, 2019
In light of a well-renowned report, “The Future of Nursing” released by the Institute of Medicine (2010), recommendations were suggested that nurses should practice at, and to, the full extent of their licensure, also referred to as top-of-license ...
Dickerson, Michelle
core   +1 more source

Indian Journal of Critical Care Medicine

, 2022
Shrikanth Srinivasan, Praveen G Kumar, Deepak Govil, Sachin Gupta, Vivek Kumar, Kishore Pichamuthu, Anuj M Clerk, Amol Kothekar, Pradeep M D'Costa, Kedar Toraskar, Kapil Dev Soni, Jojo K John, Sweta J Patel, Raymond Dominic Savio, K N Jagadeesh, Chacko Jose, Rahul Pandit, Palepu Gopal, Dhruva Chaudhry, Subhal Dixit, Rajesh Mishra, Arindam Kar, Srinivas Samavedam   +22 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source