Results 181 to 190 of about 2,745,548 (338)

Targeting Multiple Pathophysiological Axes in COPD: Nanomaterial Advances

open access: yesInternational Journal of Nanomedicine
Qianyue Zhang,1,* Shuanglan Xu,2,* Chunyan Yang,3,* Xiaolan Wang,1 Ting Liu,1 Xinting Zhang,2 Chongchang Qu,2 Jiawang Wu,1 Jiao Yang,4 Xiqian Xing2 1Kunming Medical University, Kunming, Yunnan, 650500, People’s Republic of China ...
Zhang Q   +9 more
doaj  

Cognitive Load in Pediatric Critical Care Medicine: Tsunamis and a Thousand Cuts. [PDF]

open access: yesCrit Care Explor
Ehrmann DE   +8 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Geriatric Critical Care Medicine

open access: yesJournal of the Indian Academy of Geriatrics, 2019
Arvind Mathur
doaj  

The Cross-Sectional Area of Erector Spinae Muscles Obtained from Chest CT Is an Independent Predictor of Death in COPD

open access: yesInternational Journal of COPD
Jin Liu, Rui Li, Yuer Li, Shaobo Ge, Shiyuan Yao, Rui Zhang, Hongyan Fu, Pu Ning, Jie Zhang, Ming Zhang Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic ...
Liu J   +9 more
doaj  

Multicountry survey of emergency and critical care medicine physicians’ fluid resuscitation practices for adult patients with early septic shock [PDF]

open access: gold, 2016
Lauralyn McIntyre   +18 more
openalex   +1 more source

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