Results 21 to 30 of about 2,745,548 (338)

miR-181a-5p Inhibits Pyroptosis in Sepsis-Induced Acute Kidney Injury through Downregulation of NEK7

Journal of Immunology Research, 2022
Sepsis is a life-threatening organ dysfunction caused by the uncontrolled inflammation, easily affecting the kidney. Sepsis-induced acute kidney injury (S-AKI) has high morbidity and mortality, of which the pathophysiological mechanisms have not been ...
Meng Zhang, Deyuan Zhi, Jin Lin, Pei Liu, Yajun Wang, Meili Duan   +5 more
doaj   +1 more source

mTOR Modulates the Endoplasmic Reticulum Stress-Induced CD4+ T Cell Apoptosis Mediated by ROS in Septic Immunosuppression

Mediators of Inflammation, 2022
Introduction. When sepsis attacks the body, the excessive reactive oxygen species (ROS) production can result to endoplasmic reticulum stress (ERS) and eventually cause lymphocyte apoptosis.
Hao Wang, Jianwei Chen, Guangxu Bai, Wen Han, Ran Guo, Na Cui   +5 more
doaj   +1 more source

Lateral Ventricular Volume Asymmetry and Optic Nerve Sheath Diameter Predict Intracranial Pressure in Traumatic Brain Injury Patients

Applied Bionics and Biomechanics, 2022
Background. Various noninvasive methods of intracranial pressure (ICP) measurement have been proposed. Each has unique advantages and limitations. This study was aimed at investigating the relationships between lateral ventricular asymmetry on admission ...
Yang Wang, Ziming Yuan, Zuoyan Zhang, Jiawei Shang, Mingna Li, Wei Wang   +5 more
doaj   +1 more source

Neutrophil-Lymphocyte Ratio in Patients with Hypertriglyceridemic Pancreatitis Predicts Persistent Organ Failure

Gastroenterology Research and Practice, 2022
Background. The neutrophil–lymphocyte ratio (NLR) has been proposed as a surrogate marker of inflammation with prognostic value in various diseases. Our objective was to investigate the predictive value of the NLR as an indicator of persistent organ ...
Zhihua Lu, Xiangping Chen, Huiqing Ge, Man Li, Binbin Feng, Donghai Wang, Feng Guo   +6 more
doaj   +1 more source

Nomograms for Predicting Coexisting Cardiovascular Disease and Prognosis in Chronic Obstructive Pulmonary Disease: A Study Based on NHANES Data

Canadian Respiratory Journal, 2022
Background. Chronic obstructive pulmonary disease (COPD) is a common chronic disease. Progression is further exacerbated by the coexistence of cardiovascular disease (CVD).
Yuanjie Qiu, Yan Wang, Nirui Shen, Qingting Wang, Limin Chai, Jian Wang, Qianqian Zhang, Yuqian Chen, Jin Liu, Danyang Li, Huan Chen, Manxiang Li   +11 more
doaj   +1 more source

Smoking Status Modifies the Relationship between Th2 Biomarkers and Small Airway Obstruction in Asthma

Canadian Respiratory Journal, 2021
Background. Cigarette smoking and Th2-inflammation are both crucial in the pathogenesis of asthma. However, it is unknown whether smoking can affect the association between Th2-inflammation and small airway obstruction in adults with asthma.
Shuyuan Chu, Libing Ma, Jianghong Wei, Jiying Wang, Qing Xu, Meixi Chen, Ming Jiang, Miao Luo, Jingjie Wu, Lin Mai, Guofang Tang, Biwen Mo   +11 more
doaj   +1 more source

Personalized Critical Care Medicine (Review)

Общая реаниматология, 2022
Personalized medicine (PM) is a major trend in health care development in the 21st century. This area includes studying risk factors for disease development (prediction), interventions for preventing diseases (prophylaxis), individualization of diagnosis
A. M. Golubev
doaj   +1 more source

General Practitioners' perceptions of the route to evidence-based medicine: a questionnaire survey [PDF]

, 1998
Objectives: To determine the attitude of general practitioners towards evidence based medicine and their related educational needs. Design: A questionnaire study of general practitioners.
Field, Jenny, McColl, Alastair, Smith, Helen, White, Peter   +3 more
core   +3 more sources

Critical Care Medicine [PDF]

Respirology, 2012
Critical care medicine is a multidisciplinary branch of medicine encompassing the provision of organ support to patients who are severely ill. All areas of medicine may have relevance for critically ill patients; however, this review focuses only on aspects of cardiopulmonary monitoring, life support, technologic ...
openaire   +2 more sources

Teaching paediatric critical care medicine to paediatric residents [PDF]

, 2010
Critical care training during paediatric residency provides an ideal opportunity to learn and refine the skills needed in the early recognition and prompt treatment of the acutely ill paediatric patients. Paediatric critical care medicine is a relatively
Haider, Rizwan, Haque, Anwarul, Salat, Muhammad Sohail   +2 more
core   +1 more source