Results 91 to 100 of about 22,219,108 (275)

Encapsulated Leptin‐Producing Cells Facilitate Entrainment of Circadian Rhythms in Rodents and Nonhuman Primates

Advanced Science, EarlyView.
A clinically translatable cell line can be engineered to produce leptin, encapsulated in biomaterial and safely implanted to produce and deliver the metabolic regulating protein within the body. Implantation of these encapsulated cells decreases the time it takes for mice and non‐human primates to adjust to circadian disruptions similar to those ...
Samantha T. Fleury, Xuanyi Lin, Peter D. Rios, Christopher Olker, Eun Joo Song, Alejandra Cobos Perez, Cody Fell, Daisy Lopez, Ira Joshi, Hafsa Nasir, Cecelia Curtis, Danna Muringi, Kaiyuan Wang, José Oberholzer, Fred W. Turek, Isaac B. Hilton, Jonathan Rivnay, Martha Hotz Vitaterna, Omid Veiseh   +18 more
wiley   +1 more source

Reflection 3 [PDF]

, 2009
ICIS Peripheral Project,The Historical,Geographical and Anthropological Research School of Thanh Ha in the Outer Port of Hue,Vietnam, Column1:To Read with the Heart or from the Face?, The Second ICIS International Symposium Construction of Cultural ...
4738, Institute, For Cultural Interaction Studies Kansai University, 4742   +2 more
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From 1990 to 2004: Reflections on movements in cultural studies [PDF]

, 2006
This article contains reflections on the 1990 cultural studies conference held at theUniversity of Illinois and some observations onwhere I perceive cul- tural studies appear to havemoved or aremoving in the period leading up to the 2004 crossroads ...
Lynch, R
core   +1 more source

CDK4/MERCs/PINK1 Axis Drives PFOA/HFPO‐TA‐Induced Cardiac Senescence via Mitophagy Defect and cGAS‐STING Activation: In Vitro Amelioration by Cycloastragenol

Advanced Science, EarlyView.
The present study demonstrated that PFOA and HFPO‐TA exposure suppressed CDK4, disrupted MERCs and impaired PINK1/Parkin‐mediated mitophagy, thereby accelerating cardiac senescence, whereas CAG effectively reversed these pathological changes in vitro. Our findings identify CDK4 as a critical regulator bridging mitophagy defects and cardiac senescence ...
Nuo‐Wa Li, Jun‐Ze Jiang, Ying‐Ying Liu, Tian‐Tian Zhang, Kanwar Kumar Malhi, Xin Yao, Jin‐Long Li   +6 more
wiley   +1 more source

SynNotch Receptors for Visualizing Immunoreceptor Force Transmission and Downstream Signaling In Vivo

Advanced Science, EarlyView.
A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li, Jintian Lyu, Kaitao Li, Ameya Dravid, Deepali Balasubramani, Amir H. K. Ashkezari, Hyun‐Kyu Choi, Gabriel A. Kwong, Ankur Singh, Cheng Zhu   +9 more
wiley   +1 more source

Decoding Viral Transmission Dynamics in Structured Populations Using a Microfluidic Herd‐Immunity‐on‐a‐Chip Platform

Advanced Science, EarlyView.
A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang, Narina Jung, Min‐Hyeok Kim, Wanyoung Lim, Zhenzhong Chen, Byung Mook Weon, Sungsu Park   +6 more
wiley   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Women's Leadership in South African Higher Education: A Systematic Review of Research Trends, Methodological Approaches, and Transformation Challenges (2010-2024)

International Journal of Contemporary Educational Research
This systematic review examines research trends on women's leadership in South African higher education from 2010 to 2024, analyzing 98 academic works comprising 15 doctoral dissertations, 28 master's theses, and 55 journal articles.
Preya Pillay
doaj   +1 more source

Determinants of Health Behavior in Public Health Promotion: A Critical Review

Jurnal Kesehatan Budi Luhur
Health behavior is a major determinant of individual and population health and is shaped by multiple interacting factors across different levels of influence.
Nur Ekawati, Pusfitasari, Andi Asrina, Yusriani, Fairus Prihatin Idris   +4 more
doaj   +1 more source

Policy Quarterly special issue: Global studies: The challenge of governance in the 21st century

, 2017
Editorial: Whereas the November 2016 issue of Policy Quarterly focused on local government, this issue takes a global perspective. In particular, it explores the major challenges facing humanity in the 21st century, and it does so through the lens of ...
Institute for Governance and Policy Studies (VUW)
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