Results 121 to 130 of about 24,804,093 (330)
Development of the instrumentation of the botafoc breakwater nº 8 caisson [PDF]
Balearic Port Authority has developed an instrumentation system for the #8 caisson of the Botafoc breakwater that integrates 12 pressure sensors located at three surfaces, two in contact with the sea water and another with the bottom.
Almazan Garate, Jose Luis +3 more
core +1 more source
Quench protection analysis in accelerator magnets, a review of the tools
As accelerator magnets see the increase of their magnetic field and stored energy, quench protection becomes a critical part of the magnet design. Due to the complexity of the quench phenomenon interweaving magnetic, electrical and thermal analysis, the ...
Felice, H., Todesco, E.
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Successful communication is vital for the success of any design project. However, communication often fails, adversely affecting design process efficiency and product quality.understand the connections between different aspects of design and don–t know ...
Clarkson, P. J. +2 more
core
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Exemplary Design Research [PDF]
In this paper, we will look at what role a research program and an interventionist research strategy based on design experiments may play for the advancement of knowledge relevant to design and designers.
Binder, Thomas, Redström, Johan
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The Effect of Problem Based Learning Model on Critical Thinking Skills in the Context of Chemical Reaction Rate [PDF]
The previous research result showed that the learning model based on the investigation could increase the students' critical thinking skills. The aim of this research was to measure the effectiveness of the using of problem-based learning model to ...
Dakabesi, D. -. (Daud) +1 more
core
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source

