Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Critical Design Strategy of Thermogalvanic Hydrogels for Low-Grade Heat Harvesting. [PDF]
Adv Sci (Weinh)Lin W +7 more
europepmc +1 more source
3D collagen fibrillar microstructure guides pancreatic cancer cell phenotype and serves as a critical design parameter for phenotypic models of EMT. [PDF]
PLoS One, 2017 Puls TJ +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Critical Design Parameters of Tantalum-Based Comb Structures to Manipulate Mammalian Cell Morphology. [PDF]
Materials (Basel)Moussa HI +5 more
europepmc +1 more source
Systematic review of acute physically active learning and classroom movement breaks on children's physical activity, cognition, academic performance and classroom behaviour: understanding critical design features. [PDF]
BMJ Open Sport Exerc Med, 2018 Daly-Smith AJ +5 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Critical Design and Characterization Methodology for a Homemade Three-Axis Fluxgate Magnetometer Measuring Ultra-Low Magnetic Fields. [PDF]
Sensors (Basel)Can H +6 more
europepmc +1 more source
Critical design aspects involved in the study of Paneth cells and the intestinal microbiota. [PDF]
Gut Microbes, 2014 Shanahan MT, Carroll IM, Gulati AS.
europepmc +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source