Results 41 to 50 of about 25,486,006 (176)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A critical analysis of media discourse on the South African broadband policy [PDF]
Broadband Internet access promises a number of socio-economic benefits to citizens of developing countries like South Africa (SA). However poor policy outcomes of Information and Communication Technology (ICT), particularly in the area of poverty ...
Vergeer, Johannes Willem
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Higher Education Institutions’ Responses to Risk: A Critical Discourse Analysis [PDF]
Increased concerns about students who present a risk to self or others have been documented in the literature since the 1990s. In particular, concern has been expressed about students who self-harm and students with mental health difficulties (for a ...
Harrison Woods, Paula L
core +3 more sources
A critical analysis of women’s and men’s public discourse on climate change [PDF]
openEcolinguistics is a fairly recent branch of linguistics which intends to highlight the link between the language of a community and the ecosystem (both natural and cultural) in which it lives, that can differ and vary according to cultural features ...
PIZZARELLI, ALESSIA
core
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Discourse Analysis in Tourism Research: A critical perspective [PDF]
© 2005 Tourism Recreation Research. Increasing numbers of researchers in the field of tourism studies are using discourse analysis as a means of critical investigation when faced with qualitative or textual forms of data, such as written documents, or ...
Hannam, Kevin, Knox, Dan
core +1 more source

