Results 71 to 80 of about 127,761 (298)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Global capitalism and critical awareness of language. [PDF]
, 1999 As the shape of the new global social order becomes clearer, so too does the need for a critical awareness of language as part of language education. I discuss, with a focus on discourse, several key features of late modern society which help make the ...
Fairclough, Norman, Norman Fairclough
core
Bulletin of Taras Shevchenko National University of Kyiv. Literary Studies. Linguistics. Folklore StudiesBackground. This article examines the complementarity and potential for innovative synthesis of critical discourse analysis and cognitive linguistics through a literature review. Given the longstanding issue of the lack of cognitive explanation in critical discourse analysis and the weakness of the social dimension in cognitive linguistics, the study ...
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Critical discourse analysis and the problem of methodology
, 2009 The question of methodology in Critical Discourse Analysis (CDA) is complex and emergent as the field grows and develops after coming to prominence as a major arm of the broader field of discourse analysis over the past decade or so.
Otsuji, E, Lee, A
core
Press, Ideological Discourse and Coup d'Etat: a Critical Discourse Analysis
Revista Eletrônica de Ciência Administrativa, 2019 Inserted in the broader context of the historical organizational studies (Maclean, Harvey, & Clegg, 2016), the present work had as objective to analyze the Special Notebook “64 – Brazil Continues” from the Folha de São Paulo (FSP) Journal in the light of
Cynthia Adrielle da Silva Santos +1 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Introduction to Critical Discourse Analysis
, 2020 In this video, Drs.
Jennifer deWinter +2 more
core +1 more source
Marx's critique of ideology for discourse analysis: from analysis of ideologies to social critique [PDF]
, 2018 The notion of ideology is related to social and material reality and especially to the processes of social reproduction. Therefore, the analysis of ideology seems to fall into the domain of discourse analysis.
Herzog, Benno, Benno Herzog
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source