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The Critical Distance for the Cycloaromatization Reactions of Enediynes

Current Topics in Medicinal Chemistry, 2008
It has been shown that the enediyne anticancer antibiotics e.g., calicheamicin, neocarzinostatin and others cleave DNA via the putative intermediate 1,4-diradical formed in the Bergmann cyclization and are thus useful for cancer chemotherapy. The pharmacological activity of these drugs is based, in general, on the activation of the pharmacophore and ...
Joseph F, Capitani   +3 more
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Critical approach distances and critical angles for channelling

Radiation Effects, 1971
Abstract The critical angles and critical approach distances, which determine the limits for the channelling of energetic ions, down open crystal directions are established by the methods of computer simulation and compared with simple analytical models. For non-vibrating rows or planes a good agreement between the two is obtained.
D. Vernon Morgan, Dirck Van Vliet
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A (Critical) Distance

2017
The increase in demand for higher education has resulted in a surge of online courses and degree programs across the US and worldwide. Calls for open access learning options and more cost-effective higher educational opportunities have contributed to this rapid increase, especially in the form of Massive Open Online Courses, or MOOCs. For educators and
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Teaching critical thinking at a distance

Distance Education, 1989
(1989). Teaching critical thinking at a distance. Distance Education: Vol. 10, No. 1, pp. 135-147.
Marshall Hopkins, Mary Richardson
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Critical Distance: Creative Writing as a Critic-Fan

2021
Writing reviews of other people’s work is a highly engaging, but often challenging, form of creative writing. The critic needs to be aware of a variety of styles and comfortable working with constraints, balancing their own voice with that of the artist whose work they are reviewing.
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Definition of Critical Distance

1994
Figure 17 is the first of many that will relate direct and reverberant field measurements in large enclosed spaces. The equation that gives the reduction in sound pressure as we move away from a point source is as follows:
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Critical distances in proton diffraction

Physics Letters A, 1967
Abstract A calculation of critical distances for proton diffraction in channeling experiments indicates that the diffracted wave cannot be neglected.
R.E. DeWames, W.F. Hall, L.T. Chadderton
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Tracking Point-Curve Critical Distances

2006
This paper presents a novel approach to continuously and robustly tracking critical (geometrically, perpendicular and/or extremal) distances from a moving plane point $p \in \mathbb R^2$ to a static parametrized piecewise rational curve γ(s) ($s \in \mathbb R$).
Xianming Chen   +2 more
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Critical Reflections in Distance Education

2020
This chapter argues a case for critical reflection in distance education, especially in relation to teaching practices. By teaching practices the people mean that range of activities which is conventionally associated with terms such as curriculum, course development, examination, assessment, tutoring, course writing, pedagogy, andragogy and teaching ...
Terry Evans, Daryl Nation
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Critical Distances | Distances critiques

2015
L’architecture semble avoir récemment subi un processus de dé-consécration, une sorte de sécularisation. C’est comme si elle avait perdu le pouvoir de représenter son cadre institutionnel, ou son sens de la communauté ; comme si elle avait été dépossédée de son rôle. Dans ce contexte, le point de vue du critique en architecture est de moins
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