ABSTRACT Aim Persistent high‐risk HPV infection can lead to the development of precancerous lesions, potentially progressing to invasive cancer. HPV status serves not only as a prognostic marker for squamous cell carcinoma (HNSCC) like oropharyngeal squamous cell carcinomas (OPSCC) but also significantly influences clinical management and treatment ...
Min Wang +9 more
wiley +1 more source
The Potential Role of Verapamil Against Fluconazole-Induced Torsade de Pointes: A Critical Review. [PDF]
Abdel-Razik NE +7 more
europepmc +1 more source
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang +2 more
wiley +1 more source
Developing a Fundamental Theoretical Definition for Athletic Injury: Metaphysics, Logic, and Mathematics. [PDF]
Kalkhoven JT.
europepmc +1 more source
ABSTRACT Public organisations often experience a discrepancy between improvements in technical efficiency and stakeholders' perceptions of integrity and performance. This study analyses the mechanisms that may underlie this efficiency–perception discrepancy in Spanish Defence Delegations during 2020–2023.
José Solana‐Ibáñez +1 more
wiley +1 more source
A history of addiction through the six editions of Kandel's <i>Principles of Neural Science</i> and their scientific context. [PDF]
Santiago-Martinez P +5 more
europepmc +1 more source
Empowering teachers and fostering pupil climate action in Welsh primary schools
Abstract The Curriculum for Wales intends to help students understand and address climate change, but relies on teachers' knowledge and implementation thereof. This article focuses on “The Lifecycle of My Clothes”, a unit of work (UoW) developed by academics and practitioners. The UoW aimed to increase students' awareness of the environmental impact of
Jennifer A. Rudd +2 more
wiley +1 more source
Strengthening healthy ageing in the Caribbean through regional capacity building and ICOPE implementation. [PDF]
Simo N +3 more
europepmc +1 more source
Mature T‐cell leukemia/lymphoma with an NK‐like immunophenotype: A report of 7 cases
Abstract Distinguishing T‐cell from NK‐cell neoplasms can occasionally be challenging, as neoplastic T cells can lose T‐cell markers such as surface CD3 (sCD3) and CD5 while acquiring NK‐cell markers such as CD16, CD56, and CD94. In this study, we present a series of 7 mature T‐cell lymphoma/leukemia cases with NK‐like immunophenotypes to clarify ...
Wei J. Wang +8 more
wiley +1 more source
Building public health leadership: design, implementation and outcomes of the WHO European autumn school on quality of care and patient safety. [PDF]
Fonseca VR +16 more
europepmc +1 more source

