Results 101 to 110 of about 7,557,575 (382)
Cell death and life in cancer: mathematical modeling of cell fate decisions
, 2011 Tumor development is characterized by a compromised balance between cell life and death decision mechanisms, which are tighly regulated in normal cells.
Barillot, Emmanuel +4 more
core +2 more sources
Journal of Responsible Innovation, 2019 One of the main contentions of the framework for Responsible Innovation (RI) is that social and ethical aspects have to be addressed by deliberative engagement with stakeholders and the wider publi...
Teunis Brand, V. Blok
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Implementing Guided Inquiry Learning and Measuring Engagement Using an Electronic Health Record System in an Online Setting [PDF]
, 2018 In many courses, practical hands-on experience is critical for knowledge construction. In the traditional lab setting, this construction is easy to observe through student engagement.
Maity, Pallavi +2 more
core
Linking academic emotions and student engagement: mature-aged distance students’ transition to university [PDF]
, 2015 This is an Accepted Manuscript of an article published by Taylor & Francis in Journal of Further and Higher Education on 2013, available online: https://www.tandfonline.com/doi/full/10.1080/0309877X.2014.895305Research into both student engagement and ...
Kahu, E, Leach, L, Stephens, C, Zepke, N
core +1 more source
A critical analysis of the effects of Twitter on student engagement and grades [PDF]
, 2023 Ibrahim Abdullah Alshaye +2 more
openalex +1 more source
Feminist Praxis Revisited: Critical Reflections on University-Community Engagement
Atlantis, 2020 Book under review: Dean, Amber, Johnson, Jennifer L., and Susanne Luhmann, eds. 2019. Feminist Praxis Revisited: Critical Reflections on University-Community Engagement. Waterloo: Wilfred Laurier Press.
Jennifer Musial
doaj