Results 121 to 130 of about 7,557,575 (382)

Age and connection to nature: when is engagement critical?

Frontiers in Ecology and the Environment, 2019
Conservation organizations are increasingly aware of the need to motivate pro‐environmental behavior by connecting people with nature. However, to maximize the effectiveness of the limited resources available, there needs to be a better understanding of ...
Joelene Hughes, Mike Rogerson, J. Barton, R. Bragg   +3 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The Model of Associations Between Self-Assessed Critical Thinking Skills, Their Perceived Importance and Work Engagement

Social Welfare: Interdisciplinary Approach
he purpose of this study was to explore the links between the perceived importance of critical thinking skills, self-reported critical thinking skills, and work engagement.
Aistė Diržytė , Justinas Sadauskas, Valdonė Indrašienė , Violeta Jegelevičienė, Odeta Merfeldaitė , Daiva Penkauskienė , Jolanta Pivorienė , Asta Railienė   +7 more
doaj   +1 more source

Collective narratives and politics in the contemporary study of work : the new management practices debate [PDF]

, 2011
In this article we explore the question of how as sociologists of work we might research those who constitute the substance of our labour process. We approach this question through an examination of the New Management Practices debate, principally in the
Martinez Lucio, M., Stewart, Paul
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Engagement in the social context of the neighbourhood: A critical ethnographic study of older adults with age-related vision loss

, 2021
Colleen McGrath, Carri Hand
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

'Fostering critical engagement rather than blind devotion': calling for transdisciplinary microbiology research. [PDF]

Environ Microbiol, 2021
Barendse SB.
europepmc   +1 more source

Playing simplicity: polemical stupidity in the writing of the French Enlightenment [PDF]

, 2002
Polemical stupidity - a critical concept drawn from Bakhtin – denotes the strategic refusal to understand. It appears most familiarly in the character of the Fool (like Candide), who genuinely does not understand the world, thus unmasking its ...
Howells, Robin
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source