Results 121 to 130 of about 14,752 (304)

Mobility of oculomotor system and lability of visual analyzer in patients with primary open-angle glaucoma

open access: yesJournal of Ophthalmology, 2016
Purpose: to perform a comparative assessment of oculomotor system mobility and visual system lability in patients with primary open-angle glaucoma (POAG) of stages II and III with compensated IOP.
V.A. Putienko, V.S. Ponomarchuk
doaj   +1 more source

The stroboscopic human vision [PDF]

open access: yes, 2010
When the frequency of seeing light from a pair of point flashes is beyond the probability summation of the separate flashes, the surplus is due to the successful interaction of subliminal responses from the different flashes.
Maarten A. Bouman
core   +1 more source

CD3ɛ Nanobody‐Engineered Extracellular Vesicles Driving In Vivo Generation of BiTE‐Secreting CAR‐Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity

open access: yesAdvanced Science, EarlyView.
HEK‐293T‐derived CD3ε Nb‐engineered EVs to generate dual‐targeting CAR‐T cells directly in vivo. These EVs selectively deliver CAR.BiTE transgenes into T cells and reprogramed to HLA‐G/PD‐L1‐targeting effector cells with enhanced memory and persistence.
Shi‐Wei Huang   +27 more
wiley   +1 more source

Exposure of man to low intensity magnetic fields in a coil system [PDF]

open access: yes
Physiological and psychological effects of prolonged exposure to low intensity magnetic ...
Beischer, D. E.   +2 more
core   +1 more source

PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao   +24 more
wiley   +1 more source

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

open access: yesAdvanced Science, EarlyView.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao   +12 more
wiley   +1 more source

Skin‐Inspired Design of Self‐Healing Coatings Integrating Interface‐Liquid Repellency and Corrosion Resistance

open access: yesAdvanced Science, EarlyView.
A skin‐inspired multilayered coating system is developed to integrate multiple, often conflicting, functions of self‐healing capability, strong liquid repellency, long‐term corrosion resistance, and robust adhesion, to tackle diverse challenges in engineering services.
Bingzhi Li   +8 more
wiley   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

open access: yesAdvanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su   +18 more
wiley   +1 more source

Engineering data compendium. Human perception and performance. User's guide [PDF]

open access: yes
The concept underlying the Engineering Data Compendium was the product of a research and development program (Integrated Perceptual Information for Designers project) aimed at facilitating the application of basic research findings in human performance ...
Boff, Kenneth R., Lincoln, Janet E.
core   +1 more source

Synergistic Effects of Solid Electrolyte Mild Sintering and Lithium Surface Passivation for Enhanced Lithium Metal Cycling in All‐Solid‐State Batteries

open access: yesAdvanced Science, EarlyView.
This study proposes a synergistic strategy combining mild sintering of solid electrolyte pellets with lithium metal surface passivation, effectively suppressing dendrite growth, and enhancing interfacial stability. This approach doubles the critical current density of symmetric cells (1.1 to 2.2 mA cm−2) and extends full cells cycle life at 1 mA cm−2 ...
Jinsong Zhang   +3 more
wiley   +1 more source

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