DYRK1A modulates fear memory formation via epigenetic modification. [PDF]
Mol BrainKang DS, Koo JW.
europepmc +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
Computations of Critical Groups at a Degenerate Critical Point for Strongly Indefinite Functionals
, 2001 Yuxia Guo
openalex +1 more source
Dissecting clinical features of COVID-19 in a cohort of 21,312 acute care patients. [PDF]
Commun Med (Lond)Maguire C +9 more
europepmc +1 more source
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
Association of mortality and physician experience in prehospital anaesthesia: a registry study on new physicians in Finnish helicopter emergency medical services. [PDF]
Scand J Trauma Resusc Emerg MedSaviluoto A +5 more
europepmc +1 more source
Aging and Cancer, EarlyView.ABSTRACT Purpose To assess the long‐term effects of a community cancer exercise program on quality of life, fatigue, weight, waist circumference, physical activity levels, lower extremity strength, body mass index (BMI), heart rate, and blood pressure, across non‐metastatic and metastatic patients.
Isaac Oppong, Roozbeh Naemi
wiley +1 more source
Crime Against History: Slavery, Race, and the 1776 Report
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT With the 2025 executive order, “Ending Radical Indoctrination in K‐12 Schooling,” the Trump administration reestablished the 1776 Commission, which produced The 1776 Report. This article argues that this report, which is an unsubtle response to The 1619 Project, reveals how White Christian Nationalists wish to mandate that a hyper‐patriotic ...
William V. Trollinger
wiley +1 more source
Consideration on the Critical Group, with Respect to Radioactive Waste Management
, 2002 Toshiso Kosako +7 more
openalex +2 more sources