Results 41 to 50 of about 2,498,418 (268)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Critical swimming speed in groups of Atlantic salmon Salmo salar

open access: yesAquaculture Environment Interactions, 2016
Critical swimming speed (Ucrit) has traditionally been measured in relatively small swimming tunnels with 1 fish alone. However, both increased flume lengths and swimming in groups are known to improve performance.
M Remen   +7 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Multiplicity results for the Kirchhoff type equation via critical groups

open access: yesBoundary Value Problems, 2018
In this paper, we will compute critical groups at zero for the Kirchhoff type equation using the property that critical groups are invariant under homotopies preserving isolatedness of critical points.
Zhenting Wang   +3 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Estimates for critical groups of solutions to quasilinear elliptic systems

open access: yesElectronic Journal of Differential Equations, 2003
In this work we study a class of functionals, defined on Banach spaces, associated with quasilinear elliptic systems. Firstly, we prove some regularity results about the critical points of such functionals and then we estimate the critical groups in each
Jose Carmona   +2 more
doaj  

Existence and multiplicity of solutions for a class of superlinear p-Laplacian equations

open access: yesAdvances in Nonlinear Analysis
In this work, we investigate a class of pp-Laplacian equations with the Dirichlet boundary condition. Under some new conditions, the existence and multiplicity of nontrivial solutions are proved by means of the variational methods.
Zhao Tai-Jin, Li Chun
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

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