Results 71 to 80 of about 2,498,418 (268)
Balancing selfishness and norm conformity can explain human behavior in large-scale prisoner's dilemma games and can poise human groups near criticality [PDF]
John Realpe-Gómez +3 more
openalex +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Mateusz Michał Tomczyk,1 Sławomir Boncel,1 Artur Herman,2 Tomasz Krawczyk,1 Agata Jakóbik-Kolon,1 Mirosława Pawlyta,3 Maciej Krzywiecki,4 Artur Chrobak,5 Masafumi Minoshima,6 Fuminori Sugihara,7 Kazuya Kikuchi,6 Nikodem Kuźnik1 1Faculty of ...
Tomczyk MM +11 more
doaj
Geodesic distance for right-invariant metrics on diffeomorphism groups: critical Sobolev exponents [PDF]
Robert L. Jerrard, Cy Maor
openalex +1 more source
BISCIT: Biliary Interventions in critically ill patients with Secondary Sclerosing Cholangitis – a study protocol for a multicenter, randomized, controlled parallel group trial [PDF]
Klaus Stahl +16 more
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
An asymmetric problem at resonance with a one-sided Ahmad-Lazer-Paul condition
Leandro L. Recova, Adolfo J. Rumbos
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AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Despite the modest regional consumption of organic products, Sicily is one of the most important European regions in surface area per number of companies active in organic farming.
Giorgio Schifani +3 more
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