Results 31 to 40 of about 2,015,439 (266)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

How proinflammatory cytokines may impair growth and cause muscle wasting

open access: yes, 2007
Background: Cytokines, such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-1 beta and IL-6, that are released in response to injury are thought to inhibit growth and cause muscle wasting, at least in part by inhibiting anabolic hormones such as ...
Thissen, Jean-Paul   +1 more
core   +1 more source

Critical issues in the MBE growth of Ga0.47In0.53As for waveguide/PIN/JFET integration

open access: yes, 2022
S.1084-1088The critical issues for the optimization of the MBE grown layer sequence for the integration of an optical waveguide, a PIN photodiode and a junction field effect transistor (JFET) to form a monolithical integrated receiver chip are discussed.
Kunzel, H.   +4 more
core   +1 more source

Critical telomerase activity for uncontrolled cell growth [PDF]

open access: yesPhysical Biology, 2016
The lengths of the telomere regions of chromosomes in a population of cells are modelled using a chemical master equation formalism, from which the evolution of the average number of cells of each telomere length is extracted. In particular, the role of the telomere-elongating enzyme telomerase on these dynamics is investigated.
Wesch, Neil L   +2 more
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

On the Concept of Green Growth and the Role of Policy and Public Finance [PDF]

open access: yes, 2016
This article aims to identify the current discussion on green growth, and focuses on the role of public finance in promoting a transition towards green growth.
Sudo, Tomonori, 936
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

On Kirchhoff Problems Involving Critical Exponent and Critical Growth [PDF]

open access: yesJournal of Applied Mathematics and Physics, 2019
In this paper, we establish the existence of multiple solutions to a class of Kirchhoff type equations involving critical exponent, concave term and critical growth. Our main tools are the Nehari manifold and mountain pass theorem.
Mohammed El Mokhtar O. El Mokhtar   +1 more
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

FDI and Growth in Vietnam: A Critical Survey

open access: yesJournal of Economics and Development, 2013
More than ever, countries at all levels of development seek to leverage FDI for development and adopt measures aimed at improving their investment climate. Despite the exhaustive literature on the topic however, results on growth effects of FDI still remain controversial.
Tran, Thi Anh-Dao, Dinh, Thi Thanh Binh
openaire   +2 more sources

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