Results 41 to 50 of about 7,454,737 (295)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Vulnerability modeling and analysis for critical infrastructure protection applications

open access: yes, 2013
Effective critical infrastructure protection requires methodologies and tools for the automated evaluation of the vulnerabilities of assets and the efficacy of protection systems.
F. De Cillis   +12 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Extending the cyber-attack landscape for SCADA-based critical infrastructure

open access: yes, 2019
The move from point-to-point serial communication to traditional information technology (IT) networks has created new challenges in providing cyber-security for supervisory control and data acquisition (SCADA) systems in critical infrastructure.
Foo, E, Radke, K, Rodofile, NR
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Australian infrastructure audit [PDF]

open access: yes, 2015
Examines the drivers of future infrastructure demand, particularly population and economic growth. Summary The Australian Infrastructure Audit takes a strategic approach to assessing our nation\u27s infrastructure needs.
Infrastructure Australia
core  

Cyber-Attacks Against Critical Infrastructure

open access: yes, 2022
In the cyber world, the most important threat focuses on critical infrastructure (CI). CI encompasses the structures and functions that are vital to society’s uninterrupted functioning.
Lehto, Martti
core   +1 more source

ECONOMIC MEASURES FOR MANAGING CRITICAL INFRASTRUCTURE FACILITIES IN UKRAINE

open access: yesBaltic Journal of Economic Studies, 2023
Purpose. This article defines the variety of economic measures for the management of critical infrastructure objects. Attention is paid to their nature and characteristics, and it is shown how they affect the area under study.
Bohdan Bohdana   +2 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

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