Results 121 to 130 of about 18,400 (244)

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Critical Legal Theory Today

, 2009
This essay, written for a book on jurisprudence in America today, asks what the critical tradition in American jurisprudence means today in the light of the events of the past 30 years.Critical theories ask how law legitimates power in both senses of the
Balkin, Jack M
core  

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

Advanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi, Hao Jia, Jianfei Dong, Linhao Li, Jingqi Cao, Xun Chen, Zhenzhen Jia, Jing Na, Zhijie Yang, Xinyuan Chen, Yubo Fan, Shuhua Yue, Lisha Zheng   +12 more
wiley   +1 more source

Critical Legal Studies

, 2022
Constitutional police regulation is a complex tangle of substantive rights, remedies, and procedural rules. Together, they appear to scaffold a cohesive system of police restraint.
Sekhon, Nirej
core  

Femtosecond‐Laser‐Induced Physical Unclonable Random Maze Structure for Storage‐Free Encryption

Advanced Science, EarlyView.
Femtosecond‐laser‐induced gold random maze structures serve as multimodal physical unclonable functions for storage‐free encryption. Their stochastic optical, electrical, and Raman responses are generated by plasmon‐assisted Marangoni formation and converted into AES‐compatible keys without permanent secret‐key storage, offering a portable route toward
Shiru Jiang, Hongliang Li, Shengjie Ma, Sang‐Shin Lee, Lei Wang, Mengyun Hu, Heping Zeng   +6 more
wiley   +1 more source

The Criminal Procedure Code (KUHAP) as an Instrument for Assessing Judges’ Compliance with the 10 Points of the Code of Ethics and Guidelines for Judges’ Conduct (KEPPH) in Criminal Trials

Journal of Mathematics Instruction, Social Research and Opinion
This study analyzes the position of Law Number 20 of 2025 concerning the Criminal Procedure Code (KUHAP 2025) as an instrument for assessing judges’ compliance with the 10 Points of the Code of Ethics and Guidelines for Judges’ Conduct (KEPPH) in ...
Junaidi Syamfran
doaj   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

Advanced Science, EarlyView.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami, Masanori Ono, Yasunari Mizumoto, Tatsuhito Kanda, Takashi Iizuka, Takiko Daikoku, Shin‐ichi Horike, Akira Hattori, Akihito Horie, Sachiko Minamiguchi, Tomoko Fujiwara, Kazuyoshi Hosomichi, Atsushi Tajima, Hirokazu Usui, Kaoru Abiko, Hiroshi Fujiwara   +15 more
wiley   +1 more source

On The Critical Legal Studies Movement

, 1985
The present study critically examines the account of legal thought developed in Roberto Unger\u27s very long article, The Critical Legal Studies Movement (1983), and tests it against Unger\u27s own account of certain exemplary difficulties in the
Finnis, John M., Finnis, J.M.
core   +1 more source

Legal Pluralism, Plurality of Laws, and Legal Practices [PDF]

, 2007
Issue on 'Cross-perspectives'Published online: 01 September 2007Legal pluralism has become a major theme in socio-legal studies. However, under this very broad denomination, one can identify many different trends which share little but the very basic ...
DUPRET, Baudouin
core  

Consideraciones para un análisis ideológico del derecho a partir de los Critical Legal Studies

Estudios de Derecho
El presente artículo pretende exponer algunas consideraciones para fundamentar un análisis ideológico crítico del derecho a partir de los Critical Legal Studies (CLS).
Felipe Villa García
doaj