Results 31 to 40 of about 363,721 (294)

Questions à Jacques Caillosse

open access: yesCahiers Jean Moulin, 2017
Les travaux de Jacques Caillosse se singularisent dans le champ du droit administratif par une approche croisant de multiples savoirs avec une grande originalité.
Jacques Caillosse, Lionel Zevounou
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

PENDEKATAN GEOGRAFI HUKUM KRITIS DALAM KAJIAN HUKUM TATA RUANG INDONESIA: SEBUAH WACANA FILSAFAT HUKUM DAN INTERDISIPLIN

open access: yesJustitia Et Pax, 2021
The development of legal research shows the importance of an interdisciplinary approach in examining legal issues. Apart from that, legal issues also need to be examined more critically and not to see them as a product of a vacuum without the influence ...
Victor Imanuel W. Nalle
doaj   +1 more source

You cannot eat critique : on uncritical critical (legal) theory and the poverty of bullshit [PDF]

open access: yes, 2021
Published online: 09 June 2021This article reflects upon critical theory, focusing especially on critical legal theory, particularly in relation to human rights.
EVANS, Matthew, Matthew Evans (8444262)
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

“Critical Empiricism” in American Legal Studies: paradox, program, or pandora's box?

open access: yesBrazilian Journal of Empirical Legal Studies, 2014
In this article, David Trubek and John Esser analyze the proposal of “critical empiricism” suggested by scholars of the Amherst Seminar in the United States. Based on the review of the scholarship produced by the Amherst group, the authors identify their
David Max Trubek, John Esser
doaj   +1 more source

Entanglements in Legal History [PDF]

open access: yes, 2014
"Legal History presents a broad panorama of historical processes that trigger theoretical reflections on legal transfers and legal transplants and on the problem of the reception and assimilation laws and other modes of normativity. In this volume, legal
Castro, Fernández   +17 more
core   +1 more source

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