Results 161 to 170 of about 107,923 (299)

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Long-term outcomes of autologous cell transplantation for patients with non-TAO autoimmune disease-related critical limb ischemia. [PDF]

Cell Transplant
Liu H, Zou L, Fang Y, Fang G, Liu Y, Jiang X, Chen B, Wei Z, Gu S, Liu P, Fu W, Pan T, Dong Z.   +12 more
europepmc   +1 more source

Diffuse dermal angiomatosis of the thigh as the presenting sign of critical limb ischemia. [PDF]

J Vasc Surg Cases Innov Tech, 2023
Pillai GS, Shah SS, Ferringer T, Salzler GG, Ryer EJ.   +4 more
europepmc   +1 more source

Pharmacological treatment with a GABA(A) receptor modulator and a selective serotonin reuptake inhibitor as a mitigation strategy against aircraft noise‐induced cardiovascular and neuronal damage

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić, Marin Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Hans‐Georg Buchholz, Nicole Bausbacher, Simon Lange, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Axel Methner, Sebastian Steven, Huige Li, Mathias Schreckenberger, Dilja Krueger‐Burg, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber   +25 more
wiley   +1 more source

Bypass surgery in a Jehovah's Witness with critical limb ischemia and end stage renal disease: a case report. [PDF]

J Surg Case Rep
Choi E.
europepmc   +1 more source

Therapeutic potential of small molecules that block receptor‐induced Kv7/M‐current suppression in neuroprotection, seizures, and pain

British Journal of Pharmacology, EarlyView.
Receptor‐induced Kv7/M‐current suppression increases neuronal activity and contributes to pathology of several conditions. A new class of Kv7 modulators identified in this study attenuates M‐current suppression and shows therapeutic effects. Abstract Background and Purpose Neuronal Kv7 channels generate low voltage–gated potassium currents known as the
Young Woo Kim, Pavan Kumar Behara, Lamees Alhassen, Cindy Wong, Olivier Civelli, Naoto Hoshi   +5 more
wiley   +1 more source

Next‐Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS

Cell Proliferation, EarlyView.
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang, Jinrui Li, Xingjia Mao, Wanyu Wang, Yansong Li, Xuefei Hu, Jinjie Zhong, Fengdong Zhao, Linlin Wang   +8 more
wiley   +1 more source

Adipose-derived dual cell therapy enhances arteriogenesis and limb preservation through vascular integration in critical limb ischemia. [PDF]

NPJ Regen Med
Kim DY, Hwang DY, Park G, Song YJ, Kang J, Son Y, Yim SV, Hong HS.   +7 more
europepmc   +1 more source

Racial and Ethnic Disparities in Treatment of Critical Limb Ischemia: A National Perspective. [PDF]

J Am Heart Assoc, 2023
Wahood W, Duval S, Takahashi EA, Secemsky EA, Misra S.   +4 more
europepmc   +1 more source

Sarcopenia as a Prognostic Factor for Critical Limb Ischemia: A Prospective Cohort Study. [PDF]

J Clin Med
Luque-Linero P, Frutos-Reoyo EJ, Castilla-Guerra L, Rico-Corral MÁ, Salamanca-Bautista P, Garrachón-Vallo F.   +5 more
europepmc   +1 more source