Results 191 to 200 of about 39,076 (258)

Investigational New Drug-enabling studies to use genetically modified mesenchymal stromal cells in patients with critical limb ischemia. [PDF]

Stem Cells Transl Med
Cressman A, Le B, Morales D, Yen WS, Wu FJ, Perotti NH, Fury B, Nolta JA, Fierro FA.   +8 more
europepmc   +1 more source

Blood flow restriction: The acute effects of body tilting and reduced gravity analogues on limb occlusion pressure

Experimental Physiology, EarlyView.
Abstract Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP.
Patrick Swain, Nick Caplan, Luke Hughes
wiley   +1 more source

Critical Limb Ischemia Due to Suspected Buerger's Disease in an Adolescent Patient: A Case Report. [PDF]

Cureus
Silvestri O, Luongo A, Benenati A, Turchino D, Portella P, Bracale UM.   +5 more
europepmc   +1 more source

Differential intestinal injury and unchanged systemic inflammatory responses to leg and whole‐body passive hyperthermia in healthy humans

Experimental Physiology, EarlyView.
Abstract Hyperthermia can cause intestinal injury, facilitating endotoxin translocation and an inflammatory response that has been associated with heat illness. However, the potential occurrence of these responses has been incompletely reported during passive hyperthermia, and the independent effect of hyperthermia is equivocal.
Oliver R. Gibson, Orlando Laitano, Kazuhito Watanabe, José González‐Alonso   +3 more
wiley   +1 more source

Study protocol for a randomized clinical trial evaluating the safety and efficacy of autologous adipose-derived stem cell therapy for ulcers in patients with critical limb ischemia. [PDF]

PLoS One
Oliveira Filho FJ, Rodrigues LDS, Amaral SMBD, Mellucci Filho PL, Medolago NB, de Carvalho Bovolato AL, Alvarado RC, Bertanha M.   +7 more
europepmc   +1 more source

Optimizing cerebrovascular endothelial health through shear stress modulation

Experimental Physiology, EarlyView.
Abstract The endothelium plays a pivotal role in regulating cerebrovascular blood flow, and its dysfunction increases the risk of cerebrovascular disease. Endothelial shear stress, a primary mechanical stimulus for endothelial nitric oxide production, is a key modulator of vascular adaptation.
Erika Iwamoto, Rintaro Sakamoto, Darren P. Casey   +2 more
wiley   +1 more source

Technical Pitfalls and Tips of Management for Critical Limb Ischemia by Distal Bypass Using the Autogenous Veins. [PDF]

Ann Vasc Dis
Kokubo T, Okata S, Natsume K, Sasajima T.   +3 more
europepmc   +1 more source

Blood flow restriction exercise during microgravity exposure in parabolic flight

Experimental Physiology, EarlyView.
Abstract This case report evaluates whether it is possible to perform blood flow restriction (BFR) exercise during exposure to microgravity. The objectives were three‐fold: (1) to determine if a personalised tourniquet system (PTS) hardware technology performs nominally and enables BFR exercise in microgravity; (2) to determine if BFR augments the ...
Yannick Laflamme, Etienne Chassé, Luke Hughes   +2 more
wiley   +1 more source

A Phase 1/2a Clinical Trial to Evaluate the Efficacy and Safety of Allogenic Adipose Tissue-Derived Mesenchymal Stem Cell Clusters in Patients with Critical Limb Ischemia. [PDF]

Int J Stem Cells
Park YM, Park JK, Kim HS, Yang SS, Kim JW, Kim DI.   +5 more
europepmc   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source