MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
A Call for Contextualization: Is Cardiopulmonary Exercise Testing the Gold Standard for Exercise Capacity? [PDF]
Sitko S +3 more
europepmc +1 more source
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Algorithmic inclusion? The role of AI-assisted inclusive leadership in shaping gendered outcomes in multicultural academic teams. [PDF]
Tahir I +4 more
europepmc +1 more source
Critical Homogeneous Metrics on the Heisenberg Manifold
application/pdf Let H be the Heisenberg group and let Γ be the discrete subgroup of H with integer entries. We obtain a necessary and sufficient condition for a homogeneous metric g on H/Γ to be a critical point for the total scalar curvature functional I defined for the set A(M) of some proper homogeneous Riemannian metrics on H/Γ. 紀要類(bulletin) 77709
openaire
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
EPreNet: A Condition-Guided Network Accelerates Etching Profile Prediction. [PDF]
Lu M, Jin Z, Wang W, He J, Liu Q.
europepmc +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
A perspective and demonstration of an approach to screening synthetic nucleic acid orders containing short nucleic acid sequences. [PDF]
Gemler BT +6 more
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source

