Results 111 to 120 of about 2,119,910 (291)
Machine learning models for the elastic-critical buckling moment of sinusoidal corrugated web beam
Results in EngineeringThe torsional stiffness of I-beams with sinusoidal corrugated web is higher than that of flat web beams and the accuracy of the available hand-calculation methods to determine the elastic critical lateral-torsional buckling moment depends on the ...
Gábor Hajdú +2 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Siła Krytyczna Ramienia Dźwigu przy Wyboczeniu z Płaszczyzny Zawieszenia
Engineering Transactions, 1967 The usual method for computing the critical force of a bar with luffing rope for buckling out of the plane of suspension was, until recently, the same as for a bar fixed at its lower end the upper end remaining free.
W. Dmitrijuk
doaj
Case Studies in Construction MaterialsDiaphragm walls have been widely applied in long-span suspension bridges due to superior mechanical performance and extensive adaptability to various geological conditions.
Jia Wang, Wen Xiong, C.S. Cai
doaj +1 more source
Elastic Critical Moment for the Lateral-Torsional Buckling (LTB) Analysis of Structural Glass Beams with Discrete Mechanical Lateral Restraints. [PDF]
Materials (Basel), 2020 Santo D, Mattei S, Bedon C.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source