Results 131 to 140 of about 7,163,355 (354)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Traces of tricritical dynamics beyond SSB in finite-size systems undergoing second-order phase transition: the case of the 3D Ising model

open access: yesFrontiers in Complex Systems
In finite-size thermal systems that exhibit second-order phase transition, the fluctuations of the order parameter ϕn obey type I intermittent dynamics at their pseudocritical temperature Tpc.
Yiannis Contoyiannis   +5 more
doaj   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

open access: yesAdvanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez   +8 more
wiley   +1 more source

Multiple‐Instance Superparameterization: 1. Concept, and Predictability of Precipitation

open access: yesJournal of Advances in Modeling Earth Systems, 2019
We have investigated the predictability of precipitation using a new configuration of the superparameterized Community Atmosphere Model (SP‐CAM). The new configuration, called the multiple‐instance SP‐CAM, or MP‐CAM, uses the average heating and drying ...
Todd R. Jones   +2 more
doaj   +1 more source

The Critical Conditions of Filtration Flow Blocking in a Porous Channel with Phase Transitions [PDF]

open access: yesJournal of Heat and Mass Transfer Research
The paper studies the occurrence of kinetic phase transitions in porous media with thermodynamic phase transitions, which affect filtration flow through permeability or viscosity: in the simplest case, permeability is a step function of local temperature.
Igor Donskoy
doaj   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

open access: yesAdvanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo   +8 more
wiley   +1 more source

Field-Theoretic Techniques in the Study of Critical Phenomena [PDF]

open access: yes, 1997
We shortly illustrate how the field-theoretic approach to critical phenomena takes place in the more complete Wilson theory of renormalization and qualitatively discuss its domain of validity.
Bagnuls, C., Bervillier, C.
core   +2 more sources

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

open access: yesAdvanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen   +4 more
wiley   +1 more source

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