Results 61 to 70 of about 361,254 (268)
Investigating and Completing Khanlari’s Theory on Metrical Units [PDF]
Literary ArtsMetrical units have a special place in the study of prosody, and as such, scholars have always paid particular attention to their scansion and naming.
Abbas Jahed Jah
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Deficits in Processing Case Markers in Individuals with Aphasia
Frontiers in Psychology, 2015 Introduction People with aphasia (PWA) presented sentence processing deficits (Berndt et al, 1997; Caplan & Hildebrandt, 1988). However, linguistic features associated with sentence processing deficits might differ across languages.
Jee Eun Sung, Kyeong Ok Mo
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Intersectionality queer studies and hybridity: methodological frameworks for social research [PDF]
, 2012 This article seeks to draw links between intersectionality and queer studies as epistemological strands by examining their common methodological tasks and by tracing some similar difficulties of translating theory into research methods. Intersectionality
Fotopoulou, Aristea
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Wild vertebrates and their representation by urban/rural students in a region of northeast Brazil
Journal of Ethnobiology and Ethnomedicine, 2019 Background Recognition of the diversity of living beings, including the classification and naming of species, is a fundamental condition for biological literacy with the aim of developing critical awareness of human relationships with nature, and for ...
José Valberto de Oliveira +5 more
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Imagining and emplacing net zero industrial clusters: A critical analysis of stakeholder discourses
Geo: Geography and EnvironmentDecarbonizing industrial sectors is a critical global challenge, involving the creation of new industrial spaces—‘net zero industrial clusters’—co‐locating energy sectors and ‘hard‐to‐abate’ industries such as oil refining and steelmaking.
Huei‐Ling Lai, Patrick Devine‐Wright
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