Results 81 to 90 of about 361,254 (268)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

David Brackett. 2016. Categorizing Sound: Genre and Twentieth-Century Popular Music. Berkeley: University of California Press

open access: yesCurrent Musicology, 2018
In Categorizing Sound, David Brackett presents a broad and richly detailed “history of the practice of categorizing” popular music in the twentieth century (331), asking when, how, and why stylistic labels and classification schemes become legible across
Thomas Johnson
doaj   +1 more source

Race riots on the beach: A case for criminalising hate speech? [PDF]

open access: yes, 2008
noThis paper analyses the verbal and textual hostility employed by rioters, politicians and the media in Sydney (Australia) in December 2005 in the battle over Sutherland Shire¿s Cronulla Beach.
Asquith, Nicole
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Naming and Framing Difficult Issues to Make Sound Decisions [PDF]

open access: yes, 2011
Outlines how to promote shared decision making and effective collective action by naming divisive community issues in ways that focus on common concerns, deliberating over options, identifying actions citizens can take, and working through ...

core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Casting And Recasting Gender: Children Constituting Social Identities Through Literacy Practices [PDF]

open access: yes, 2002
Considers how gender, identity and literacy are entangled and mutually constitutive. Concludes that social experience, desire, proximate others, and the ways in which children can draw upon these in the classroom are aspects of the situated condition ...
Anderson, Diane Downer
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Engaging in Toponymic Justice: Proactively Naming The Nishihara Family Classroom

open access: yesIn the Library with the Lead Pipe
In Brief: Toponyms, or place names, which situate a location in its historical, social, and demographic context, are reconsidered during efforts to establish toponymic justice, a re-naming lens arising out of critical place-name studies.
Natalia Fernández   +2 more
doaj  

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