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3D-printed scaffolds with ROS-clearing capacity for critical-sized bone defect regeneration

Biomaterials Advances
The repair of critical-size bone defects remains a major challenge in the field of biomedical tissue rehabilitation. Within the injured tissue microenvironment, inflammation and cellular apoptosis trigger the accumulation of reactive oxygen species (ROS), thereby impeding tissue regeneration.
Pengfei, Chen   +5 more
openaire   +2 more sources

3D-printed polymeric scaffolds with optimized architecture to repair a sheep metatarsal critical-size bone defect

2022
Abstract The reconstruction of critical-size bone defects in long bones remains a challenge for clinicians. We developed a new bioactive medical device for long bone repair by combining a 3D-printed architectured cylindrical scaffold made of clinical-grade polylactic acid (PLA) with a polyelectrolyte film coating ...
Charlotte Garot   +19 more
openaire   +1 more source

Three-Dimensional-Printed Spherical Hollow Structural Scaffolds for Guiding Critical-Sized Bone Regeneration

ACS Biomaterials Science & Engineering
The treatment of bone tissue defects continues to be a complex medical issue. Recently, three-dimensional (3D)-printed scaffold technology for bone tissue engineering (BTE) has emerged as an important therapeutic approach for bone defect repair. Despite the potential of BTE scaffolds to contribute to long-term bone reconstruction, there are certain ...
Xiao Liu   +9 more
openaire   +2 more sources

Three-Dimensionally Printed Hyperelastic Bone Scaffolds Accelerate Bone Regeneration in Critical-Size Calvarial Bone Defects

Plastic & Reconstructive Surgery, 2019
Background: Autologous bone grafts remain the gold standard for craniofacial reconstruction despite limitations of donor-site availability and morbidity. A myriad of commercial bone substitutes and allografts are available, yet no product has gained widespread use because of inferior clinical outcomes. The ideal bone substitute
Yu-Hui, Huang   +7 more
openaire   +2 more sources

Outcomes of Surgical Reconstruction Using Custom 3D-Printed Porous Titanium Implants for Critical-Sized Bone Defects of the Foot and Ankle

Foot & Ankle International, 2022
Background: Treating critically sized defects (CSDs) of bone remains a significant challenge in foot and ankle surgery. Custom 3D-printed implants are being offered to a small but growing subset of patients as a salvage procedure in lieu of traditional alternates such as structural allografts after the patient has failed prior procedures. The long-term
Bijan Abar   +6 more
openaire   +2 more sources

Multidimensional Resonance Controlled by Critical Size in Printed Binary Colloidal Crystals for High-Contrast Imaging

Journal of the American Chemical Society
Colloidal crystal engineering enables the precise construction of structures with remarkable properties. However, the flexible and synergistic regulation of multiple properties of colloidal crystals remains a significant challenge. Here, we inspire from Brazilian opals to self-assemble polymer nanoparticles in the gaps of a single-layer opal substrate ...
Xu Yang   +14 more
openaire   +2 more sources

3D printing of strontium-doped hydroxyapatite based composite scaffolds for repairing critical-sized rabbit calvarial defects

Biomedical Materials, 2018
In this study, strontium substituted hydroxyapatite (Sr-HAP) was synthesized using collagen type I and citrate as bi-templates and the obtained nanoparticles with high similarity to natural bone minerals were made into composite scaffolds with interconnected porous structure using a three-dimensional (3D) printing technique.
Yun Luo, Shangsi Chen, Yufei Shi, Jun Ma
openaire   +2 more sources

Layered Antimicrobial Selenium Nanoparticle–Calcium Phosphate Coating on 3D Printed Scaffolds Enhanced Bone Formation in Critical Size Defects

ACS Applied Materials & Interfaces, 2020
Preventing bacterial colonization on scaffolds while supporting tissue formation is highly desirable in tissue engineering as bacterial infection remains a clinically significant risk to any implanted biomaterials. Elemental selenium (Se0) nanoparticles have emerged as a promising antimicrobial biomaterial without tissue cell toxicity, yet it remains ...
Cedryck Vaquette   +2 more
openaire   +5 more sources

Critical size of crack propagation from residual void in micro via in printed wiring boards

2010 Proceedings 60th Electronic Components and Technology Conference (ECTC), 2010
The micro-via was fabricated with diameter of 200 to 400μm, inner hole plate thickness of 18μm, hole land thickness of 18 to 20μm, and solder resist thickness of 13μm on hole land. We investigated that the size of residual void increased as that of micro-via increased; also, dominance of micro-via cracking was observed when temperature was applied at ...
openaire   +1 more source

Three-dimensional printed strontium-containing mesoporous bioactive glass scaffolds for repairing rat critical-sized calvarial defects

Acta Biomaterialia, 2015
The development of a new generation of biomaterials with high osteogenic ability for fast osseointegration with host bone is being intensively investigated. In this study, we have fabricated three-dimensional (3-D) strontium-containing mesoporous bioactive glass (Sr-MBG) scaffolds by a 3-D printing technique.
Shichang, Zhao   +7 more
openaire   +2 more sources

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