Results 151 to 160 of about 1,606,935 (294)
A generalized expression for the ratio of the critical temperature to the critical pressure with the van der Waals surface area [PDF]
, 1997 Yakoumis, IV +7 more
core +1 more source
Critical random graphs : limiting constructions and distributional properties [PDF]
, 2010 We consider the Erdos-Renyi random graph G(n, p) inside the critical window, where p = 1/n + lambda n(-4/3) for some lambda is an element of R. We proved in Addario-Berry et al.
Goldschmidt, C. (Christina) +6 more
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Approach for Monitoring and Measurement of Interdependent Services in Critical Infrastructures [PDF]
This paper presents a systematic approach for computing metrics and performance indices of interdependent critical infrastructures based on their information content, expert views and risk analysis capabilities.
Zabašta, Anatolijs, Kuņicina, Nadežda
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Critical properties of a random transverse crystal field Ising model with bond dilution
Open Physics, 2011 Wen Ling, Shi-Lei Yan
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
A Morse-type index for critical points of vector functions [PDF]
In this work we study the critical points of vector functions form Rn to Rm with n m, following the definition introduced by S. Smale in the context of vector optimization.
Rocca Matteo +2 more
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source