Results 71 to 80 of about 4,402,031 (267)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Critical view of anaphylaxis epidemiology: open questions and new perspectives

open access: yesAllergy, Asthma & Clinical Immunology, 2018
In contrast to the majority of allergic or hypersensitivity conditions, worldwide anaphylaxis epidemiological data remain sparse with low accuracy, which hampers comparable morbidity statistics.
Luciana Kase Tanno   +12 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Variations on the Theme of Journe's Lemma [PDF]

open access: yes, 2005
Journe's Lemma is a critical component of many questions related to the product ${BMO}$ theory of S.-Y. Chang and R. Fefferman. This article presents several different variants of the Lemma, some known, some implicit in the literature, and some new ...
C. Pipher   +6 more
core   +5 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

On things seen and unseen: enlarging the vision in sociology of religion [PDF]

open access: yes, 2017
Our earliest sociological forebears gave us big ideas to think with and often turned their foundational questions to the analysis of religion. Durkheim (1964) asked how the energy of a gathered community became condensed into symbols that endure and bind
Ammerman, Nancy T.
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Academic Freedom and Society: Some Critical Questions

open access: yesExchanges, 2017
A review of a recent one-day conference, Academic Freedom and Society, held on June 2 2017 at the University of Warwick, which sought to pose questions about ideals and practices of academic freedom, historically and in the current moment, across ...
Lara Choksey
doaj  

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