Results 1 to 10 of about 34,532 (296)
Oil Imag(e)inaries: Critical Realism and the Oil Sands
Imaginations: Journal of Cross-Cultural Media Studies, 2012 eng
Imre Szeman, Maria Whiteman
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
‘A realist theory of art history’. Review of: Ian Verstegen, A Realist Theory of Art History (Ontological Explorations), London and New York: Routledge 2013 [PDF]
Journal of Art Historiography, 2013 Until recently, art history has been dominated by anti-realist and social-constructivist ideologies—arguably, in a more radical form than this has been the case in other fields of the humanities. Ian Verstegen’s book A Realist theory of Art History is an
Branko Mitrović
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Converting Consumerism: A Liturgical-Ethical Application of Critical Realism
Religions, 2019 Critical realism as a lens of thought is not new to theological inquiry, but recently a growing number of theologians have been using its conceptual frameworks to guide their thought on how social structures function theologically, and how ethics might ...
Benjamin Durheim
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Based on Critical Realism A Critique of Sadr's Islamic Economics Theory [PDF]
حکمت معاصر, 2013 This paper studies the capability and capacity of critical realism in justifying Sadr’s Islamic Economics theory from methodological individualism point of view.
Seyed Mohammad Reza Amiri Tehrani +1 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
CoSMO, 2016 The essay presents the traits of what has recently been called new realism in philosophy, arguing that this new trend aims at engaging with the existence of certain classes of objects, trying to avoid devolving to scientific thinking all questions about ...
Maurizio Ferraris
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
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