Results 61 to 70 of about 5,804,570 (326)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Assessment of Visual Function in Patients Undergoing Prone Positioning for COVID-19-Related ARDS: A Qualitative Observational Study

Anesthesia Research
Background/Objectives: Prone positioning is a key strategy to improve oxygenation in ARDS patients, particularly used during the COVID-19 pandemic. However, its impact on visual function remains poorly investigated.
Iacopo Cappellini, Elena Schirru, Laura Vannucci, Federico Scandagli, Vittorio Pavoni   +4 more
doaj   +1 more source

Critical Enhancement of the In-medium Nucleon-Nucleon Cross Section at low Temperatures

, 1994
The in-medium nucleon-nucleon cross section is calculated starting from the thermodynamic T-matrix at finite temperatures. The corresponding Bethe-Salpeter-equation is solved using a separable representation of the Paris nucleon-nucleon-potential.
A. Bohnet, A. Faessler, A. L. Fetter, B. E. Vonderfecht, B. ter Haar, C. A. Ogilvie, C. Q. Li, D. J. Thouless, D. Klakow, G. Rickayzen, G. Röpke, H. M. Xu, J. Cugnon, J. Haidenbauer, M. Baldo, M. Baldo, M. Baldo, M. Lacombe, M. Schmidt, M. Schmidt, O. Sjöberg, P. A. Henning, S. Schmitt Rink, T. Alm, T. Alm, T. Alm, W. Cassing, W. D. Kraeft   +27 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Identification and management of incidental findings in a Veteran’s lung cancer screening program

Respiratory Research
Background Incidental findings (IFs) are common on low dose CT obtained during lung cancer screening (LCS). The identification and management of clinically significant IFs is a challenging aspect of LCS programs and there is no standardized method of ...
Renee L. Colucci, Eric Garshick, Julie White, Emily S. Wan, Julianne O’Leary, Lisa A. Blake, Samantha M. Hoyt, Demerise Johnston, Kathleen LaCerda, Michelle Morreale-Karl, Anupma Jati, Fatima G. Wilder, Daniel C. Wiener, Justin M. Rucci, Ronald H. Goldstein   +14 more
doaj   +1 more source

Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes

Nature Communications, 2020
Ultrasensitive methods for detection of biomarkers for infectious disease are needed for diagnosing, monitoring and targeting treatment. Here the authors develop a digital assay for inflammatory markers, bacterial DNA and antibotic-resistance genes and ...
M. Fatih Abasıyanık, Krysta Wolfe, Hoang Van Phan, Jing Lin, Bharathi Laxman, Steven R. White, Philip A. Verhoef, Gökhan M. Mutlu, Bhakti Patel, Savaş Tay   +9 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Newly Described Clinical and Immunopathological Feature of Dermatitis Herpetiformis

Clinical and Developmental Immunology, 2012
Dermatitis herpetiformis (DH) is an inflammatory cutaneous disease with typical histopathological and immunopathological findings clinically characterized by intensely pruritic polymorphic lesions with a chronic-relapsing course.
Veronica Bonciolini, Diletta Bonciani, Alice Verdelli, Antonietta D'Errico, Emiliano Antiga, Paolo Fabbri, Marzia Caproni   +6 more
doaj   +1 more source

Modern vision for critical flow in an egg-shaped section [PDF]

, 2021
Lamia Hachemi Rachedi, M. Lakehal, Bachir Achour   +2 more
openalex   +1 more source