Clonal Hematopoiesis and CAR T Cell Therapy: From Biological Crosstalk to Clinical Implications
ABSTRACT Clonal hematopoiesis (CH) is increasingly recognized as a significant biological phenomenon in aging and cancer, marked by the expansion of hematopoietic stem and progenitor cells harboring somatic mutations in genes associated with myeloid neoplasms.
Wei Du +4 more
wiley +1 more source
Critical success factors for successful technology innovation development in sustainable energy enterprises. [PDF]
Alka TA, Raman R, Suresh M.
europepmc +1 more source
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed +6 more
wiley +1 more source
Identifying and assessing BIM implementation challenges and success factors in sustainable building projects among Malaysian SMEs. [PDF]
Al-Ashmori YY +5 more
europepmc +1 more source
Autoimmunity and Periodontitis
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
Analysing Lean 4.0 adoption factors towards manufacturing sustainability in SMEs: A hybrid ANN-Fuzzy ISM framework. [PDF]
Qureshi KM +5 more
europepmc +1 more source
This review describes the features of grade C molar‐incisor pattern periodontitis and discusses the role of A. actinomycetemcomitans in its pathogenesis and why molars and incisors are preferably affected. Possible future studies on this aggressive disease in primary and permanent dentition and emerging omics techniques for diagnosis and management are
Luigi Nibali +3 more
wiley +1 more source
Optimizing biometric system selection via complex spherical fuzzy einstein aggregation operators. [PDF]
Kanwal S +3 more
europepmc +1 more source
Tumor-Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities. [PDF]
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Liu Y, Nie X, Gao X.
europepmc +2 more sources
A selectivity index for public-private partnership projects in the urban water and sanitation sector in Latin America and the caribbean. [PDF]
Munoz-Jofre J +3 more
europepmc +1 more source

