Myelodysplastic Syndromes: 2026 Update on Diagnosis, Risk‐Stratification and Management
ABSTRACT Disease Overview The myelodysplastic syndromes (MDS) are a heterogeneous group of myeloid disorders characterized by peripheral blood cytopenias and increased risk of transformation to acute myelogenous leukemia (AML). MDS occurs more frequently in older males and in individuals with prior exposure to cytotoxic therapy.
Guillermo Garcia‐Manero
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Epithelial Integrins Coordinate Cellular Crosstalk Through the Regulation of Cytokines During Tissue Remodeling. [PDF]
Snyder J, Dhulipalla S, Longmate WM.
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ABSTRACT With the increasing demand for high‐quality agricultural products, the agricultural cold‐chain logistics packaging (ACLP) industry faces significant environmental pressure and circular economy issues. This study analyzes the critical success factors (CSFs) that would enhance ACLP circular economy performance (CEP). The adversarial interpretive
Miao Su +3 more
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Decoding Host-Pathogen Dynamics in <i>Klebsiella pneumoniae</i> Infections: Mechanisms of Cell Death Regulation and Host-Directed Therapies for Sepsis. [PDF]
Thomas SS +11 more
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Progressive BBB/BSCB dysfunction is increasingly recognized as both a pathological feature and a therapeutic barrier in ALS. Novel delivery technologies and barrier‐restoration strategies may enhance CNS drug exposure, improve the efficacy of disease‐modifying therapies, and advance ALS treatment. ABSTRACT Background Amyotrophic lateral sclerosis (ALS)
Nitesh Sanghai +9 more
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Translational interdisciplinary research on human chorionic gonadotropin's enhancement of neuroendocrine crosstalk: a novel medical hypothesis for systemic adjunctive treatment of psychiatric disorders. [PDF]
Gaspary JFP, Lopes LFD, Camara AG.
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Mild cognitive impairment (MCI) carries a risk of further cognitive decline; thus, early diagnosis and intervention are important. The ASCEND Expert Group presents novel algorithms for (1) cognitive assessment/clinical diagnosis and (2) MCI management, emphasizing a multimodal strategy encompassing metabolic/cerebrovascular risk reduction, sensory loss
Nagaendran Kandiah +16 more
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Corrigendum to "Decision support systems for waste-to-energy technologies: A systematic literature review of methods and future directions for sustainable implementation in Ghana" [Heliyon Volume 11, Issue 3, February 2025, Article e42353]. [PDF]
Adu TF +3 more
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Unraveling the immunosuppressive microenvironment of glioblastoma and advancements in treatment. [PDF]
Jiang D, Li Y.
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ABSTRACT Type 1 Diabetes (T1D) is an autoimmune disorder marked by the immune‐mediated destruction of pancreatic β‐cells, resulting in insulin deficiency and dysregulated glucose control. Current therapies—such as insulin replacement and artificial pancreas systems—manage symptoms but fail to restore endogenous β‐cell function or halt disease ...
Fatemeh Sabet Sarvestani +4 more
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