Results 151 to 160 of about 466,615 (301)

A model for developing improvements to critical thinking skills across the community college curriculum

, 2013
Society is faced with more complex problems than in the past because of rapid advancements in technology. These complex problems require multi-dimensional problem-solving abilities that are consistent with higher-order thinking skills.
McGarrity, DeShawn
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

A study of the development of critical thinking skills using an innovative web 2.0 tool

, 2012
BACKGROUND: Healthcare educators face numerous challenges including technological change, information overload, and the need to maintain clinical expertise and research knowledge across multiple specialities.
Cornell, J., Cornell, Jacqueline, Gillham, David, Clarke, Colin, Clarke, C., Grech, Carol, Eales-Reynolds, Lesley-Jane, Gillham, D., Grech, C., Eales-Reynolds, L.J.   +9 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

An intervention program for practising critical thinking: on-shore and off-shore students blogging together

, 2009
An intervention program was devised to assist off-shore students develop critical thinking skills through blogs. On-shore students were assisted in setting up group blogs and off-shore students engaged in discussion with the issues raised. In this manner
Hobson, J.
core  

Teaching critical thinking skills in Rwandan secondary schools: challenge and practical solutions

Cogent Education
Many university graduates struggle with critical thinking due to weak secondary school preparation, affecting their independent reasoning and decision-making.
Laurien Tuyishimire, Wallace Mlaga, Patrice Ntawigira   +2 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The Development of a Critical Thinking Conceptual Model to Enhance Critical Thinking Skills in Middle-Eastern Nurses: A Middle-Eastern Experience

, 2007
This paper aims to describe the development of a critical thinking conceptual model which was constructed to guide the teaching and evaluation of critical thinking skills to Middle-Eastern ...
Simpson, Elaine, Courtney, Mary D.
core  

Critical thinking, logic, and argument : An introduction [PDF]

I. Arguments and LanguageII. Categorical LogicIII. Informal FallaciesIV. ConclusionThinking critically is a complicated but important endeavour that involves learning how to think clearly, acquiring problem-solving skills, and applying these skills in ...
Dayton, Eric, Rodier, Kristin
core   +1 more source