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TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Network structure influences self-organized criticality in neural networks with dynamical synapses. [PDF]
Front Syst NeurosciSugimoto YA, Yadohisa H, Abe MS.
europepmc +1 more source
Privacy preserving optimization of communication networks. [PDF]
Nat CommunLei D +9 more
europepmc +1 more source
Leadership tasks in public health: findings from the National Board of Public Health Examiners' job task analysis. [PDF]
Front Public HealthDubois C +5 more
europepmc +1 more source
Cortical Mechanisms Contributing to Ketamine-Induced Dissociation. [PDF]
NeuroscientistBera K, Looger LL, Proekt A, Cichon J.
europepmc +1 more source
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Acritical Criticism, Critical Criticism
SSRN Electronic Journal, 2007This paper theorizes critical readings from an interactional / argumentative point of view, situating them on a scale going from consonant, "friendly" criticism, to dissonant, confrontational or "unfriendly" criticism. Some key critical notions (by Oscar Wilde, Stanley Fish, Paul Ricoeur, Judith Fetterley and H. Porter Abbott) are examined in the light
openaire +1 more source
Physical Review Letters, 2010
Depletion interactions and the critical Casimir effect are usually regarded as distinct phenomena in colloidal suspensions. By experimentally investigating how the Asakura-Oosawa picture, appropriate for a weakly correlated depletant, is modified when critical correlations develop within the depletion agent, we conversely show that the former merges ...
BUZZACCARO, STEFANO +3 more
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Depletion interactions and the critical Casimir effect are usually regarded as distinct phenomena in colloidal suspensions. By experimentally investigating how the Asakura-Oosawa picture, appropriate for a weakly correlated depletant, is modified when critical correlations develop within the depletion agent, we conversely show that the former merges ...
BUZZACCARO, STEFANO +3 more
openaire +3 more sources
1997
From the very beginning of his career, Arthur Miller has engaged with the critical enterprise, but perhaps even more interestingly he has himself been a relentless and passionate critic, in all of his plays, of the human social and psychological condition, and has consistently ascribed a high value to that critical engagement.
openaire +1 more source
From the very beginning of his career, Arthur Miller has engaged with the critical enterprise, but perhaps even more interestingly he has himself been a relentless and passionate critic, in all of his plays, of the human social and psychological condition, and has consistently ascribed a high value to that critical engagement.
openaire +1 more source