Results 171 to 180 of about 12,933 (265)

Dynamic adjustment algorithm of equipment maintenance cycle based on substation state operation and maintenance. [PDF]

PLoS One
Yan Y, Zhou F, Cai Z, Lu H.
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Critical quantum metrology robust against dissipation and nonadiabaticity. [PDF]

Sci Adv
Lü JH, Ning W, Wu F, Zheng RH, Chen K, Zhu X, Yang ZB, Wu HZ, Zheng SB.   +8 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Sensitivity-informed framework for enrichment distribution in MNR for thermal performance enhancement. [PDF]

Sci Rep
Aziz U, Khan H, Hussain Z, Ullah K, Shah I, Jung DW.   +5 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Toward Unified Biomarkers for Focal Epilepsy. [PDF]

J Neurosci
Wang SH, Ferrari P, Arnulfo G, Marzulli M, Degras D, Myrov V, Palva S, Nobili L, Ciuciu P, Palva JM.   +9 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Process-Related Incidents in Nuclear Medicine: A Four-Year Single-Center Retrospective Analysis to Support the Implementation of a Scenario-Based Radiopharmacy Training. [PDF]

Pharmacy (Basel)
Soualy Y, Renaud SC, Torchio J, Fouillet J, Ensenat J, Rubira L, Fersing C.   +6 more
europepmc   +1 more source

Criticality Analysis of the Lower Ionosphere Perturbations Prior to the 2016 Kumamoto (Japan) Earthquakes as Based on VLF Electromagnetic Wave Propagation Data Observed at Multiple Stations. [PDF]

Entropy (Basel), 2018
Potirakis SM, Asano T, Hayakawa M.
europepmc   +1 more source