Results 141 to 150 of about 392,999 (304)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Actors and Vehicles of Architectural Criticism (8)
, 2016 Antwerp Architectural Exhibitions as Critical Actor in Belgium 1883-1972 Ellen Van Impe Centre for Flemish Architectural Archives, Vlaamse Architectuur Instituut (Flanders Architecture Institute) During the last quarter of the nineteenth century, the ...
Mapping Architectural Criticism
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Architectural Criticism between Public Debate and Autonomous Discipline (3)
, 2016 Mapping the reception of Victor Horta: the blurring boundaries of architectural criticism, theory and history Dirk Van de Vijer Associate professor, Department of History of Art, Utrecht University From 1895 to 1905, Horta stood at the peak of his fame ...
Mapping Architectural Criticism
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Architectural Criticism between Public Debate and Autonomous Discipline (6)
, 2016 Mobilizing the Nation via Architectural Criticism : The Architectural Review “Outrage” and “Counterattack” Erdem Erten Associate Professor, Izmir Institute of Technology, Department of Architecture In June 1955, The Architectural Review’s special issue ...
Mapping Architectural Criticism
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Architectural Criticism between Public Debate and Autonomous Discipline (2)
, 2016 Architectural centers: Mediation is the new Criticism Marcela Garcia Martinez University of Geneva Architecture centers are a new type of museum institution that emerged in Europe in the early 1980s.
Mapping Architectural Criticism
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, 2020 A call for paper has been launched for the next issue of HPA – Histories of Postwar Architecture, guest edited by Hélène Jannière and Paolo Scrivano, scientific coordinators of Mapping Architectural Criticism.
Mapping Architectural Criticism
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