Results 61 to 70 of about 10,689 (263)

Revisiting Tagore’s Visit to China: Nation, Tradition, and Modernity in China and India in the Early Twentieth Century

open access: yesThe ASIANetwork Exchange: A Journal for Asian Studies in the Liberal Arts, 2011
This paper aims to discuss the historical background of Rabindranath Tagore’s visit to China in 1924, which proved to be a failure because of harsh criticism from the Chinese side.
Van Symons
doaj   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Some aspects of Adolf von Harnack’s criticism on Orthodox tradition

open access: yesHTS Teologiese Studies/Theological Studies, 2013
The aim of this article is to present the critique that Adolf von Harnack (1851–1930) formulated on the Orthodox tradition in his famous book Das Wesen des Christentums, as well as to comment on its affirmations in the context of his time and way of ...
Daniel Buda
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Triplex Usus Lectionis or On Reading the Bible Theologically, Philologically, and Spiritually

open access: yesCommunio Viatorum
This survey, reflecting two and a half centuries of biblical criticism, proposes three distinct modes of reading the Bible, each determined by the reader’s role: theological reading, practiced by conscious members of faith communities whose group and ...
Petr Sláma
doaj   +1 more source

The Chariots Of Plato. Was Plato a pragmatist?

open access: yesVértices, 2014
Through a pragmatic look of Plato’s ‘The Republic’ and the ‘Seventh Letter', I analyze the pertinence or irrelevance of anti-essentialist criticism introduced by Nietzsche and Rorty, seeking a pragmatist redescription of Plato himself.
Frederico Graniço
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

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