Results 151 to 160 of about 429,654 (310)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Signes et balises - L'édition numérique en histoire de l'art - Réalisations, projets, enjeux.

, 2012
Journée d'études, organisée par Anne-Laure Brisac-Chraïbi, le 13 janvier 2012, Auditorium de la Galerie Colbert, 2, rue Vivienne, Paris- 75002. Invisu-INHA.
Observatoire Critique
core  

The utility of a composite endpoint for tracking disease progression in Lewy body dementia. [PDF]

Alzheimers Dement (N Y)
Matar E, White SR, Taylor JP, Thomas A, McKeith I, Kane J, Lewis S, Surendranathan A, O'Brien J.   +8 more
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Critical Pragmatism as a Paradigm for Nursing Research. [PDF]

Nurs Inq
Gordon R, Kekanovich M, Zuk A, Luctkar-Flude M, Macdonald D.   +4 more
europepmc   +1 more source

Cleanyourhands Campaign: a critique of the critique

Journal of Hospital Infection, 2007
Stone, S, Slade, R, Fuller, C, McAteer, J, Cookson, B, Teare, L, Jeanes, A, Cooper, B, Roberts, J, Duckworth, G, Hayward, A, Charlett, A, Michie, S   +12 more
openaire   +2 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Séminaire Nouvelles formes d’éditorialisation : constitution du savoir et apprentissages.

, 2011
Nous attirons particulièrement l’attention sur la prochaine séance du séminaire, organisé par Invisu et Sens Public, qui se tiendra le10 février 2011, Salle Peresc, à l'iNHA, de 18h à 20h.
Observatoire Critique
core  

Barriers and facilitators to advance care planning implementation for patients with neurodegenerative diseases among Indian physicians: a mixed-methods analysis. [PDF]

BMC Health Serv Res
Singh P, Parvathy KN, Dash D, Gupta N, Ramanathan U, Gofton TE, Chou C, Desai S, Pal PK, Gursahani R, Panigrahi B, Velpandian B, Chatterjee P, Chakrawarty A, Singh A, Kushwaha S, Divya KP, Ranganathan LN, Tripathi M, Vibha D, Singh RK, Das A, Parihar J, Malhotra S, Upadhyay AD, Pathak A, Elavarasi A.   +26 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source