Results 191 to 200 of about 84,201 (265)

Human dignity, technology, and solidarity in a fractured world: why Magnifica Humanitas matters for public health. [PDF]

Eur J Public Health
Correia T, Ricciardi W, McKee M.
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

An immersive mirror: a descriptive study of peer observer and active participant experiences in simulation. [PDF]

Adv Simul (Lond)
Tutticci N, Johnston S, Ramsbotham J, Theobald K.   +3 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

The Self-Care Paradox: From Nursing Theory to Neoliberal Subjectivity. [PDF]

Nurs Inq
Kim HD, Lee H.
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Commentary: Psychology's Questionable Research Fundamentals (QRFs): key problems in quantitative psychology and psychological measurement beyond Questionable Research Practices (QRPs). [PDF]

Front Psychol
Staller MS, Koerner S.
europepmc   +1 more source

Learning to navigate interprofessional boundaries in health care. [PDF]

Med Educ
Paxino J, Noble C, Eppich W.
europepmc   +1 more source

Feasibility of implementing a multicultural curriculum through artificial intelligence: perspectives of educational science experts. [PDF]

Sci Rep
Qin H, Zhou Z.
europepmc   +1 more source