Results 81 to 90 of about 19,034 (246)

Hederagenin Attenuates Cardiac Remodeling by Targeting Phosphodiesterase 9A

Phytotherapy Research, EarlyView.
ABSTRACT Background and Aim New therapeutic strategies for heart failure are urgently needed. The protective effects of cyclic guanosine monophosphate (cGMP)—protein kinase G (PKG) pathway on heart have been widely reported. Despite phosphodiesterase 9A (PDE9A) inhibitors combating cardiac remodeling, clinically available drugs are lacking. Hederagenin
Liqian Chen, Xinghong Zhou, Yanting You, Jieyu Chen, Baizhao Peng, Yijian Deng, Shuai Ji, Ying Yang, Xiaohu Chen, Huaxi Liu, Shuxuan Yang, Hiu Yee Kwan, Wen Jin, Lei Zhang, Yuegang Wang, Xiaoshan Zhao, Yanyan Liu   +16 more
wiley   +1 more source

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

Phytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou, Jingyun Chi, Yuan Ding, Zhidi Zhang, Rui Liang, Tianhao Wang, Yan Jiang, Rujun Song, Huazhou Fu, Xizhen Zhou   +9 more
wiley   +1 more source

Real‐Time Behavior Recognition Using a Legged Robot for Animal–Robot Interaction

Journal of Field Robotics, EarlyView.
ABSTRACT Animal–robot interaction is an emerging interdisciplinary field that explores the dynamics between animals and robotic systems, as well as the design principles for effective engagement. While previous approaches have investigated animal responses to robotic stimuli, they have yet to integrate artificial intelligence (AI) for real‐time ...
Edoardo Fazzari, Donato Romano, Fabrizio Falchi, Cesare Stefanini   +3 more
wiley   +1 more source

Benthic Macroinvertebrate Recovery After Wastewater Treatment Plant Upgrades: Implications for Biomonitoring

River Research and Applications, EarlyView.
ABSTRACT During the past decade, major upgrades have been made to the Kitchener and Waterloo wastewater treatment plants (WWTPs) in the Grand River watershed in Ontario, Canada. As part of efforts to evaluate the effectiveness of these investments (>$450 M CDN), a benthic macroinvertebrate (BMI) monitoring program was initiated by sampling upstream and
Sean McLay, Mark R. Servos, Leslie M. Bragg, Dominika Celmer‐Repin, Hadi A. Dhiyebi, Azar Fattahi, Keegan A. Hicks, Edward M. Krynak, Mitchell Kay, Adam G. Yates   +9 more
wiley   +1 more source

L’émergence du concept de totalité chez Lukács (I) [PDF]

, 1991
Pelletier, Lucien
core   +4 more sources

Big Bird: A global dataset of birds in drone imagery annotated to species level

Remote Sensing in Ecology and Conservation, EarlyView.
Drones are a valuable tool for surveying birds, but manually detecting and identifying birds in drone images is costly. We assembled a diverse dataset of 23 865 images of birds captured with 21 different drones across 11 countries. We labelled 4824 of these images, detailing the location, species, posture category, age category, and sex of 49 990 birds
Joshua P. Wilson, Tatsuya Amano, Thomas Bregnballe, Alejandro Corregidor‐Castro, Roxane Francis, Diego Gallego‐García, Jarrod C. Hodgson, Landon R. Jones, César R. Luque‐Fernández, Dominik Marchowski, John McEvoy, Ann E. McKellar, W. Chris Oosthuizen, Christian Pfeifer, Martin Renner, José Hernán Sarasola, Mateo Sokač, Roberto Valle, Adam Zbyryt, Richard A. Fuller   +19 more
wiley   +1 more source

Resource reallocation across successive systemic innovations: How Rolls‐Royce shaped the evolution of the turbojet, turboprop, and turbofan

Strategic Management Journal, EarlyView.
Abstract Research Summary Despite the importance of resource reallocation in shaping a variety of strategic outcomes, strategy scholars have paid only limited attention to the processes by which firms reallocate their resources across successive systemic innovations.
Gino Cattani, Mariano Mastrogiorgio, Giuseppe Carignani   +2 more
wiley   +1 more source

Regard rapproché, regard éloigné dans la critique d’art, de Diderot à Huysmans

Modern Languages Open
Throughout his Salons, Diderot meditated on the distance from which one should view a painting. Chardin’s paintings fascinated him, transforming with every step back taken by the viewer. Form is born from matter; meaning derives from the thickness of the
Michel Delon
doaj   +1 more source

Monitoring GPS‐collared moose by ground versus drone approaches: efficiency and disturbance effects

Wildlife Biology, EarlyView.
Efficient wildlife management requires precise monitoring methods, for example to estimate population density, reproductive success, and survival. Here, we compared the efficiency of drone (equipped with a RGB camera) and ground approaches to detect and observe GPS‐collared female moose Alces alces and their calves. We also quantified how drone (n = 42)
Martin Mayer, Erlend Furuhovde, Kristoffer Nordli, Giorgia Myriam Ausilio, Petter Wabakken, Ane Eriksen, Alina L. Evans, Karen Marie Mathisen, Barbara Zimmermann   +8 more
wiley   +1 more source

Living under the scope: behavior affects survival in a heavily harvested and long‐lived ungulate

Wildlife Biology, EarlyView.
The spatiotemporal behavior of game species may play a critical role in their survival throughout the hunting season. Where humans are the most dominant predators, avoidance of landscape features that allow hunter access to hunting grounds can be key to increasing survival.
Lukas Graf, Henrik Thurfjell, Jörg Fabian Knufinke, Göran Ericsson, Wiebke Neumann   +4 more
wiley   +1 more source