Results 231 to 240 of about 4,909,303 (275)

Impact of Upper Gastrointestinal Involvement on Clinical Outcomes in Paediatric Inflammatory Bowel Disease

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to assess the clinical implications of upper gastrointestinal (UGI) involvement in paediatric inflammatory bowel disease (IBD). Methods This retrospective cohort study included children diagnosed with IBD between 2010 and 2023, who underwent a UGI endoscopic evaluation at diagnosis and were followed for at least ...
Ofek Aloni   +8 more
wiley   +1 more source

Single-Incision Laparoscopy-First Strategy in Crohn's Disease: Risk Factors for Conversion and Surgical Outcomes. [PDF]

open access: yesAnn Gastroenterol Surg
Horio Y   +9 more
europepmc   +1 more source

Inflammatory Bowel Disease Is Associated With an Increased Risk of End‐Stage Renal Disease: A Population‐Based Cohort Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In a retrospective population‐based cohort study using the University of Manitoba IBD Epidemiology Database, persons with IBD have an increased risk of ESRD by nearly 50%, with CD showing greater risk than UC. Bowel surgery, allopurinol use and oral steroid therapy are important predictors, emphasising the necessity of careful renal monitoring in IBD ...
Onuma Sattayalertyanyong   +4 more
wiley   +1 more source

Assessing the Impact of Crohn's Disease on Foot Health-Related Quality of Life: A Case-Control Study. [PDF]

open access: yesInt Wound J
Escudero-Prados JM   +8 more
europepmc   +1 more source

Impact of Prior Biologic Mechanism of Action on Anti‐TNF Effectiveness in Inflammatory Bowel Disease: An ENEIDA Registry Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this nationwide ENEIDA registry study, anti‐TNF therapy after prior exposure to a different biologic mechanism of action showed reduced treatment durability in inflammatory bowel disease, with a particularly marked impact in ulcerative colitis, where short‐ and long‐term clinical effectiveness was also lower. ABSTRACT Background The expanding use of
Carmen Yagüe Caballero   +85 more
wiley   +1 more source

Review Article: Immune Effector Cell‐Mediated Enterocolitis Following CAR‐T Cell Therapy—Clinical Features, Pathophysiology and Management

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Immune effector cell‐mediated enterocolitis is an emerging complication of CAR‐T therapy. This review summarizes its epidemiology, pathophysiology, diagnosis, endoscopic and histopathologic features, and evidence‐based management, emphasizing early recognition, multidisciplinary intervention, and step‐up therapy.
John A. Damianos   +4 more
wiley   +1 more source

Real-World Effectiveness of Risankizumab in Refractory Crohn's Disease: The RISANCROHN Study From the ENEIDA Registry. [PDF]

open access: yesAliment Pharmacol Ther
Barreiro-de Acosta M   +65 more
europepmc   +1 more source

Pruritus Is Frequent and Persistent and Impacts Quality of Life Among Patients With Primary Sclerosing Cholangitis

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Among 200 patients with primary sclerosing cholangitis, 38% reported moderate to severe pruritus in the past 6 months. During 6 months of follow up, pruritus severity fluctuated significantly. Pruritus severity was linked to worse colitis activity and lower quality of life.
Richard Dean   +16 more
wiley   +1 more source

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