Results 351 to 360 of about 9,186,337 (395)
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CYCLOSPORIN FOR CROHN'S DISEASE
The Lancet, 1984SUMMARYEight patients with active uncomplicated Crohn's disease, who were resistant to or intolerant of conventional treatment, were treated for 6 weeks with oral cyclosporin (mean dose 8.2 mg kg−1 day−1). Seven of the eight patients responded to treatment with cyclosporin by symptomatic improvement, weight gain and a return of serum C‐reactive protein
R. E. Pounder, M. C. Allison
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The Lancet
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract that might lead to progressive bowel damage and disability. The exact cause of Crohn's disease is unknown, but evidence points towards multifactorial events causing dysregulation of the innate immune system in genetically susceptible people.
Dolinger, Michael +2 more
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Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract that might lead to progressive bowel damage and disability. The exact cause of Crohn's disease is unknown, but evidence points towards multifactorial events causing dysregulation of the innate immune system in genetically susceptible people.
Dolinger, Michael +2 more
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The dilemma of Crohn's disease
Diseases of the Colon & Rectum, 1977The results of our clinical study, generally supported by the recent literature and a consensus of colorectal surgeons, indicate that an appendectomy can safely be performed in the presence of Crohn's ileitis. When fistulas do occur, they originate in the small bowel and not in the appendiceal stump.
J. Mullen +3 more
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The Lancet, 2002
Crohn's disease is a disorder mediated by T lymphocytes which arises in genetically susceptible individuals as a result of a breakdown in the regulatory constraints on mucosal immune responses to enteric bacteria. Regulation of immune reactivity to enteric antigens has improved understanding of the pathophysiological mechanisms of Crohn's disease, and ...
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Crohn's disease is a disorder mediated by T lymphocytes which arises in genetically susceptible individuals as a result of a breakdown in the regulatory constraints on mucosal immune responses to enteric bacteria. Regulation of immune reactivity to enteric antigens has improved understanding of the pathophysiological mechanisms of Crohn's disease, and ...
openaire +3 more sources
2015
Crohn’s disease (CD), with ulcerative colitis (UC) and inflammatory bowel disease unclassified (IBD-U), belongs to the group of inflammatory bowel diseases (IBD), that are chronic, idiopathic, and detrimental disorders of the gastrointestinal tract.
Salvatore Cucchiara, Marina Aloi
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Crohn’s disease (CD), with ulcerative colitis (UC) and inflammatory bowel disease unclassified (IBD-U), belongs to the group of inflammatory bowel diseases (IBD), that are chronic, idiopathic, and detrimental disorders of the gastrointestinal tract.
Salvatore Cucchiara, Marina Aloi
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Annals of the New York Academy of Sciences, 2006
Abstract: The immense microbiological load of the gastrointestinal tract poses a daunting challenge for the mucosal immune system: whereas it should tolerate the vast number of commensal bacteria, it should adequately attack pathogenic organisms. Millions of years of co‐evolution have produced an intricate system in which interactions between the ...
Daan W. Hommes +2 more
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Abstract: The immense microbiological load of the gastrointestinal tract poses a daunting challenge for the mucosal immune system: whereas it should tolerate the vast number of commensal bacteria, it should adequately attack pathogenic organisms. Millions of years of co‐evolution have produced an intricate system in which interactions between the ...
Daan W. Hommes +2 more
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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
Nature, 2001J. Hugot +19 more
semanticscholar +1 more source
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
Nature, 2001Y. Ogura +16 more
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Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1967
I. Leodolter
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I. Leodolter
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