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Immunologic Components of Hypersensitivity Reactions to Cromolyn Sodium

New England Journal of Medicine, 1975
Manifestations of cellular and humoral hypersensitivity to cromolyn sodium were sought in six asthmatic patients suspected of having acute (three cases) or subacute (three cases) adverse reactions to cromolyn inhalation. Lymphocytes from all patients produced migration inhibition factor (MIF), and those from four patients incorporated increased amounts
A L, Sheffer, R E, Rocklin, E J, Goetzl
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Cromolyn Sodium: A Review

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1985
Cromolyn is a white crystalline powder which is poorly absorbed from the gastrointestinal tract. Its therapeutic value lies in its functions as an inhaled or topically applied agent. Cromolyn has been approved in the United States for asthma therapy since 1973.
G G, Shapiro, P, König
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Sodium Cromoglycate (Cromolyn Sodium)

Drugs, 1974
Therapeutic trials of intranasal sodium cromoglycate have shown it to be of value in some patients with seasonal or perennial allergic rhinitis and in some with perennial rhinitis of unknown cause. Its use usually enables a reduction in antihistamine requirements thus, sodium cromoglycate should be useful in patients made drowsy by antihistamines.
R N, Brogden, T M, Speight, G S, Avery
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Therapy with Cromolyn Sodium

Annals of Internal Medicine, 1978
Cromolyn is a prototype of a new series of drugs, the pharmacologic activities of which may offer an entirely new approach in the treatment of asthma. Whereas bronchodilator drugs and steroids act primarily at tissue sites to counteract the effects of various toxic mediators released from tissue mast cells, cromolyn prevents the release of such ...
I. LEONARD BERNSTEIN   +2 more
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