Results 101 to 110 of about 2,294,288 (351)

Corn Cropping Systems to Improve Economic and Environmental Health [PDF]

, 2016
In 2016, UVM Extension’s Northwest Crops & Soils Program continued a multi-year trial at Borderview Research Farm in Alburgh, VT to assess the impact of corn cropping systems on overall health and productivity of the crop and soil.
Brigham, Nate, Cubins, Julija, Darby, Heather, Gupta, Abha, Ziegler, Sara   +4 more
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Cell wall proteomics of crops

Frontiers in Plant Science, 2013
Cell wall proteins play key roles in cell structure and metabolism, cell enlargement, signal transduction, responses to environmental stress, and many other physiological events.
Setsuko eKomatsu, Yuki eYanagawa
doaj   +1 more source

Effect of organic, low-input and conventional production systems on yield and diseases in winter barley [PDF]

, 2007
The effect of organic, low-input and conventional management practices on barley yield and disease incidence was assessed in field trials over two years.
Cooper, J. M., Leifert, C., Lueck, L., Schmidt, C. S., Shotton, P. N., Turnbull, C.   +5 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Results of trials with poppy seed (Papaver somniferum) in organic and integrated production technology. [PDF]

, 2010
The influence of organic and integrated management practices on poppy yield, pests and disease incidence was assessed in field trials in 2009. Crop management based on mineral fertilisers application and chemosynthetic pesticides treatment significantly
Dvorak, Petr, Hajkova, Miroslava, Kazda, Jan, Kuchtova, Perla, Plachka, Eva   +4 more
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Effect of incorporating sugar beet pulp in the finisher diet on performance of geese

Animal, 2015
The aim of this work was to study the effects of incorporating sugar beet pulp (SBP) into the diet on the development of the crop and performance of geese.
J. Arroyo, M. Brachet, J.P. Dubois, F. Lavigne, C. Molette, C. Bannelier, L. Fortun-Lamothe   +6 more
doaj   +1 more source

Crop rotations for grain production [PDF]

, 2000
There is an increasing demand for organically grown cereal grains in Denmark, which is expected to cause a change in the typical organic farm structure away from dairy farming and towards arable farming.
Askegaard, Margrethe, Olesen, Jørgen E., Rasmussen, Ilse Ankær   +2 more
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